DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and pes-23

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_509167.2	Gene:	pes-23 / 180963	WormBaseID:	WBGene00003987	Length:	520	Species:	Caenorhabditis elegans

Alignment Length:	555	Identity:	125/555 - (22%)
Similarity:	199/555 - (35%)	Gaps:	122/555 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQPNSTSLLSCSVMQFDKEFKCTSWD 80
            :|:.:  :|...|:......|.|.:.|         .:||           :.|.::..|...:.
Worm    13 FQVAM--IFMVQNVFQIYSTFGQQLKS---------TDDY-----------LQQAERVSKNDFYR 55

  Fly    81 FERESNYESITTELEWVCDDA--------YKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVL 137
            |...||:.|  |..:|:.||.        ..:|:.|    :|..:|||.|||::|..||...|..
Worm    56 FINNSNFYS--THAQWITDDTNVSVLWWENVIAIQQ----VGIFVGSILFGYISDHFGRQKVCQY 114

  Fly   138 STLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVF-- 200
            |.|..:.......|:.|....:..|||.|.......|:.:.|..|.:||:.|     .:...|
Worm   115 SLLISSVILLVEGFLSSTILIALCRFIIGTQTGAIIVVSWSLTTELISPRTR-----FLARAFAN 174

  Fly   201 YCVGLMISPWIAIWVTNWRNYLW-AASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAK 264
            :..|......|..:..|||..|. .|:....|.||:..|:.||..:|...||..:|...:..|.|
Worm   175 WPTGKFALALICFFSQNWRISLHVCAAFTLFGALLYIFFVPESPTYLQCHGKRTEAHNIVADVFK 239

  Fly   265 FNGRQVDDSVFDEFIKHYREKLNNSQNKSSDTFMGMLRTPRL--------RKF-TIILLIKSMII 320
                                   ||..|......|.:|:..|        .|: .:|:|..|:.:
Worm   240 -----------------------NSNGKCVIALPGGIRSKPLTFRQIWKKEKYRNVIILFGSIWV 281

  Fly   321 TIAFD---------ILSRNVEGVGISPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVG 376
            ...|.         |:..|  .:.:|...|......|.:..||..|.| ..|.|:.:...||.:.
Worm   282 MTNFTATMLDFSEVIIFHN--NLILSQMLLAGVPAICKILLGLVEIYF-GIISRRNLHLISLCIN 343

  Fly   377 AIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVG 441
            .|...|:|.|:......:|..:...:..:|.......:||......|.:||.|:|       .:.
Worm   344 GISMCASGVLILFGLQKNYPTIYVLVFLIGYASIEFIWDACYLCVVEQVPTEVRG-------TIS 401

  Fly   442 NAFAFFS-------SYIIYLGTFYKPLPSLMISFILLIGACLC--LALPETLHKNLPQNLEEGEM 497
            .|.:|.|       |.:..:...::|.| |.|:|...|...|.  ..|.|:...||      ||:
Worm   402 GACSFLSRLSGILASKMTIVKQRWEPAP-LFIAFATAIIHFLIAFFFLNESKDANL------GEI 459

  Fly   498 FAKGEKWYFFPCFSRRPKTQKSATQLESSDGITNK 532
                       .|:.|..:||.:.::.....:|.|
Worm   460 -----------GFTLRRISQKVSQKIHQIRNMTKK 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	117/511 (23%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	93/401 (23%)
pes-23	NP_509167.2	2A0119	<82..458	CDD:273328	99/424 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910