DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and F17C11.12

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_505789.1	Gene:	F17C11.12 / 179514	WormBaseID:	WBGene00008923	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	562	Identity:	124/562 - (22%)
Similarity:	221/562 - (39%)	Gaps:	131/562 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EKCGNFGPYQIL----------------LLGLFGYTNI------VSSLHYFSQTIISFTPSHRCS 50
            |||.|....|||                ||.:..|:.:      |:.|...|.|::..
Worm     8 EKCDNEESLQILEKTNTGTMYNTVHSDDLLKMGRYSILLCIFVEVAMLSQLSNTMLMV------- 65

  Fly    51 RPEDYQPNSTSLLSCSVMQF-DKEFKCTSWDF---ERESNYE----SITTELEWVCDDAYKLAVG 107
                |...:.::.||..|.| ..|..|..:.:   ::|..:|    .||.:.:.:|:||....:|
Worm    66 ----YAGAAPTIKSCGNMTFSSNEEACLHYSYCKEQKEMTFERQFYGITEQFKLLCEDAKLEKLG 126

  Fly   108 QSFFFIGSALGSIFFGYLADRIGR-------LPAC-VLSTLTGASGDF--FTSFVGSLPWFSFTR 162
            .|...:|..||.:.||.:.|:.||       |..| :...::..|.||  ||.|          |
Worm   127 TSIQMLGVMLGCVVFGQIGDQYGRKTPMMFCLCMCFIFGIMSALSADFKKFTIF----------R 181

  Fly   163 FISGLFMDTQYVLMYILVFEYLSPQHR-------TFGLNIILGVFYCVGLMISPWIAIWVTNWRN 220
            .|...|...|..:..:.:.|.:..:.|       ::..|:||     :|:     :|.:...|..
Worm   182 TILCFFNGGQSTISVVYMIENIPKRTRGYISTLISYSPNVIL-----LGI-----LAFFFQQWDR 236

  Fly   221 YLWAAS---LPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNG----RQVDDSVFDEF 278
            .....|   :||:.||   .|||||..||:.||:...|:|....:.||:|    :.::::..:.|
Worm   237 LALVISFLTVPAIIML---AFLHESPRWLMQKGQISHAKKVFLAIEKFDGVPAAKSLNETELENF 298

  Fly   279 IKHYREKL---NNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFK 340
            :::..:|.   .|::.....:|..:.:|..:...|.:         |||...:..:....|. |.
Worm   299 LENEHDKQVADGNTEVGKQHSFWHLFKTKEIMTGTFV---------IAFTFFATTLINYSIM-FN 353

  Fly   341 LFSYSGFCY--------------LPAGLTIILFQNKIGRK---GMACASLFVGAIITAATGYLVA 388
            |.:.:|..|              |.:||....|: |..||   |: |:.:.:..|:......|..
Worm   354 LGAVAGSIYMNSILIGLLRYSFSLFSGLLDYKFE-KFDRKMCHGI-CSVVTISIIVAIIAFCLTD 416

  Fly   389 TLDPSDYSVL--LGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYI 451
            |  .:.:|||  :|.::|.......:...:.|  :.|::||:::....:...:.......|:.::
Worm   417 T--TATFSVLIRIGVLLSCAMTSQAIIVASIA--SNELMPTAIRSISYSTAQLCSRFGIVFAPHV 477

  Fly   452 IYLGTFYK-PLPSLMISFILLIGAC----LCLALPETLHKNL 488
            .:|..:.. ..|.|..:.:|.||..    ....:|||.:|.|
Worm   478 FHLNLYTGIDFPVLPYAILLAIGLADFIFFRFLIPETKNKPL 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	121/559 (22%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	90/422 (21%)
F17C11.12	NP_505789.1	2A0119	<109..521	CDD:273328	101/450 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010