Protein Alignment CG17751 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 464
• Identity: 120/464 - (25%)
• Similarity: 197/464 - (42%)
• Gaps: 92/464 - (19%)

  Fly    96 W--VCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGR----LPACVLSTLTGASGDFFTSFVGS 154
            |  ||.|.:|:.:.|....:|..||.:..|...||.||    :.:.||:|..|||    .:...|
Human     9 WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGAS----EALAAS 69

  Fly   155 LPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWR 219
            .|.....|.:.|..:....:.:|:...|...|.|| ...::..|:|..||.::.|.:|..|.:||
Human    70 FPTLLVLRLLHGGTLAGALLALYLARLELCDPPHR-LAFSMGAGLFSVVGTLLLPGLAALVQDWR 133

  Fly   220 NYLWAASLPALGMLL----FPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIK 280
            ......:|.: |:||    ||....||..|||..|:..:|.|.|...|:.:|....||..:|
Human   134 LLQGLGALMS-GLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEE--- 194

  Fly   281 HYREKLNNSQNKSSDTFMGML--RTPRLRKFTIILLIKSMI-----ITIAFDILSRNVEGVGI-S 337
                       .|..|.:.||  |:|:.|..:.:.|:::.:     :.:.|.    ::.|.|| :
Human   195 -----------NSLATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFS----SLVGGGIRA 244

  Fly   338 PFK--LFSYSGFCYLP----AGLT------IILFQNKIGRKGMACASLFVGAIITAATGYLV--- 387
            .|:  |.......|||    |||.      ::|..:..||:.:    |.:|.::|.....|:
Human   245 SFRRSLAPQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPV----LLLGTMVTGLASLLLLAG 305

  Fly   388 ATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYII 452
            |...|. ::||  |:..||...:.......:.:|||:.||.::|.|:..:...|
Human   306 AQYLPG-WTVL--FLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAG----------- 356

  Fly   453 YLGTFYKPLPSL----------MISFILLIGACLC-LALPETLHKNLPQNLEEGEMFAKGEKWYF 506
            :||....||.:|          ::...|.:.|.|| |.|||:..:.|||:|::.:...:.
Human   357 FLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDADRLRRS----- 416

  Fly   507 FPCFSRRPK 515
             |....||:
Human   417 -PLLRGRPR 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	114/437 (26%)
		MFS	109..481	CDD:119392	104/413 (25%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	105/415 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153756
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030