DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and slc22a13

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_031760340.1	Gene:	slc22a13 / 100491580	XenbaseID:	XB-GENE-959647	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	532	Identity:	133/532 - (25%)
Similarity:	226/532 - (42%)	Gaps:	57/532 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRC-SR-------------- 51
            |...:|:..|.||.:|..|:.:....:.:::.|.|||..:.....||| ||
Frog     3 DFAEILKNVGEFGRFQKQLVVVLSLLSFLNAFHMFSQVFMEIPVPHRCDSRWILLINPNLTEAER 67

  Fly    52 -----PEDYQPNSTSLLSCSVMQFDKE----FKCTS-------WDFERESNYESITTELEWVCDD 100
                 |.|.:......|..|.:|:|.|    |...|       |:::......::.|:.:.||..
Frog    68 LNYTIPRDGRGQYEQCLMYSPVQWDMESIEKFGLNSTGPCQDGWEYDTSEQKSTLVTQFDLVCHR 132

  Fly   101 AYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLT----GASGDFFTSFVGSLPWFSFT 161
            ..:..:.||.:..|..:|::.||.|.|||||.|..:||.|.    |.|..|...|      :.:|
Frog   133 REQTGISQSVYMSGLLIGALLFGPLGDRIGRRPVILLSMLLQLVFGLSAAFAPHF------YVYT 191

  Fly   162 --RFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWA 224
              |::.|..|....:...:|..|::....|... .|...|.:.||||....::..:.|||.....
Frog   192 AFRWVVGTSMSGLMINNLVLGAEWVGSSRRACA-TITAHVCFAVGLMALAGVSYGIRNWRLLQIV 255

  Fly   225 ASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNS 289
            :|.|...:..:...|.|||.|||||||.|||.|.|:..|..|.:::.:.:..:|        |..
Frog   256 SSAPTALLFFYIWVLPESARWLLTKGKKEKAVKLLKKAAAMNKKEIPEDLLFQF--------NEE 312

  Fly   290 QNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGL 354
            ::..|...:.:.|...|||.|:::.:...:.::.:..||.||...|:..:......|...:||.:
Frog   313 KSPKSGNMIDLFRNKTLRKLTLVMCLVWFVNSLVYYGLSLNVGSFGLDIYLTQLVFGAVEIPARI 377

  Fly   355 TIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQ 419
            ..:......|||......||:|..:.     |:.|..|.:..:.:..:..:|::....::.....
Frog   378 GAMFAVQLFGRKPSQMFCLFLGGTVC-----LIITAIPRNLPIAITILAVIGKFSIASSFSICYI 437

  Fly   420 YAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETL 484
            ||||:.||.::..||....:........:..|..|..::..:|..:.....:||..||..||||.
Frog   438 YAAEVFPTVIRQNGVGLASMAARVAGITAPLISLLDKYHAAIPMAIYGSGPIIGGILCFLLPETR 502

  Fly   485 HKNLPQNLEEGE 496
            :|:|..:.::.|
Frog   503 NKDLQDHTQQDE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	130/515 (25%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	96/377 (25%)
slc22a13	XP_031760340.1	2A0119	12..509	CDD:273328	130/516 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010