DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and slc22a20p.1

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_004913725.1	Gene:	slc22a20p.1 / 100489586	XenbaseID:	XB-GENE-6463910	Length:	572	Species:	Xenopus tropicalis

Alignment Length:	580	Identity:	134/580 - (23%)
Similarity:	235/580 - (40%)	Gaps:	76/580 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRP----------EDY 55
            |....:|...|..|.:||:...:.....:....|.|.|...:..|:|||..|          :|:
Frog     1 MGFNDLLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFLQNFSAAVPAHRCWVPSLDNNTMGYDQDH 65

  Fly    56 QP------NSTSLLSCSVMQFDKEF--------------KC-TSWDFERESNYESITTELEWVCD 99
            .|      .|...|||  :::.|..              .| ..|.:::.....:|.||.:.||.
Frog    66 LPAFIPMDESEKPLSC--LRYRKALHSMWTNGTSTNHTEPCEDGWVYDKSDFSSTIVTEWDLVCK 128

  Fly   100 DAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLT----GASGDFFTSFVGSLPWFSF 160
            ......:.||.:..|..:|::..|.|:||:||....:.|.|.    |....|..:|:      ::
Frog   129 LRKMRQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIGSNLVMAVCGTCAAFLPNFI------TY 187

  Fly   161 TRF-------ISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNW 218
            ..|       .||:.::|.     .|:.|:..|:.||....:....|.| |.::...:|..:..|
Frog   188 CTFRCLCGIAFSGITLNTN-----SLILEWTPPKGRTIMGTLFAAGFTC-GQILLAALAYGIREW 246

  Fly   219 RNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDE--FIKH 281
            |...:|.|.|.....|:...:.|||.||:.||:..:|.|:|:.||..||::.:.....|  .|.|
Frog   247 RWLQFAVSAPFYFFFLYSWLVPESARWLILKGRSHEALKALQRVAIINGKREEGQKLSEMILISH 311

  Fly   282 YREKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSG 346
            .:.:||  |.|...:...:.|||.:||.||.|::......:||..|..:::..|||.|.|....|
Frog   312 MQSELN--QVKRPHSLFDLFRTPGMRKVTICLMMVWFSSGVAFYGLGMDLQNFGISIFLLQFTFG 374

  Fly   347 FCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAV 411
            ...:||.:...|....:||:......|.:..:......::     |....:|...:...|:....
Frog   375 AIDMPAKVVAALLMTYMGRRVTQATVLILSGVALLTNAFI-----PQGMKILRMVLAVFGKGCMA 434

  Fly   412 VAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACL 476
            .::.....::.|:.||.::..|:..:.::....:..:..::.|......|||.:.....:|....
Frog   435 ASFACAYLFSGELFPTVIRQTGMGVVAMMARVGSVVAPLVLLLWEISPILPSAIYGIAAIIAGGA 499

  Fly   477 CLALPETLHKNLPQNLEEGEMFAKG---------EKWYFFPCFSRR--PKTQKSATQLES 525
            ...|.||.::.||:::||.|..::|         |:.....|.|:.  ||.:....|.:|
Frog   500 ATFLMETNNQQLPESVEEVEARSQGKHTLKKVLKEEVPLNQCESQNMAPKEEMPLNQSQS 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	120/522 (23%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	89/384 (23%)
slc22a20p.1	XP_004913725.1	MFS	101..485	CDD:391944	93/402 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000