DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and slc22a16

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_002936981.2	Gene:	slc22a16 / 100488673	XenbaseID:	XB-GENE-961385	Length:	567	Species:	Xenopus tropicalis

Alignment Length:	556	Identity:	119/556 - (21%)
Similarity:	231/556 - (41%)	Gaps:	90/556 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQ----PNSTSLL 63
            ::.:.:..|:||.:|.|:.....:..|...:||.:...|:.||...|..||:..    ||:::|.
Frog     1 MERLFDYVGHFGRFQALIYFSSAFQAISCGIHYLASVFIAITPKFICRAPENISSVLLPNASTLR 65

  Fly    64 ---------------------------SCSVMQFDKE---------------FKCTSWDFERESN 86
                                       .||  :|.:|               |.|::..:...:|
Frog    66 LEDVWELWTPKDYLVVKQENGDIWELNQCS--RFKRENTSYLTYSYDGNKTLFSCSNGYYYDNTN 128

  Fly    87 YE-SITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFF-- 148
            .| ||.|:...||:..:...:.|..|..|..:|::.||.:|||:||.   ::..|| ::|.|.
Frog   129 LESSIVTDWHLVCEREWLAKLIQPTFMFGVLIGAVIFGDIADRVGRR---LILWLT-STGQFLFG 189

  Fly   149 TSFVGSLPWFSF--TRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWI 211
            .:...:..::||  .||:..:.....||::::.|.||:..:.|::. ::.:..|:.||:||...:
Frog   190 IAVAFTFDYYSFVIVRFLLAMVSSGYYVVVFVYVTEYVGIKARSWA-SMHVHAFFAVGVMIVSLV 253

  Fly   212 AIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNG--------- 267
            ...|..|..|....||..|..:|....|.|:..||.::||.::.||.:..:.|:|.
Frog   254 GFLVRTWWMYQIILSLTTLPFVLCCWMLPETPFWLYSQGKHKEVEKLIGTIEKWNKISTPCKLSE 318

  Fly   268 ----RQVDDSVFDEFIKHYREKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILS 328
                ::...:..|...||              :.:.:.......:.|:.:.:.....::.:.:.:
Frog   319 LCSVQETQKTEMDTLKKH--------------SVLDLFYNWSFARRTVTVWLIWFTGSLGYYVFA 369

  Fly   329 RNVEGVGISPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPS 393
            .|...:|.:.:.....:....:|:.:......:||||:......|.:.|:|..     :..|.|.
Frog   370 LNSVNLGGNEYLNLFLTSAVEIPSYIVACFGMDKIGRRNTLAPFLILSAVICG-----IIMLIPQ 429

  Fly   394 DYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFY 458
            |:|.:...|...|::...||:.....|.||:.||.|:...|.:..::....:..:.:.:||...:
Frog   430 DHSTVTIAMSMGGKFSIAVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRIGSVVAPFCVYLTDVW 494

  Fly   459 KPLPSLMISFILLIGACLCLALPETLHKNLPQNLEE 494
            ..:|.:::..:..:...|.|.|||||...|...:||
Frog   495 IFMPQMLVGIMAFLTGVLTLKLPETLGVPLTSTIEE 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	117/542 (22%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	80/388 (21%)
slc22a16	XP_002936981.2	MFS_SLC22A16_CT2	111..517	CDD:340933	90/429 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000