DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17751 and slc22a7b.2

DIOPT Version :9

Sequence 1:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_001337343.1	Gene:	slc22a7b.2 / 100001838	ZFINID:	ZDB-GENE-030131-9391	Length:	556	Species:	Danio rerio

Alignment Length:	555	Identity:	131/555 - (23%)
Similarity:	237/555 - (42%)	Gaps:	84/555 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLQSVLEKCGNFGPYQ--ILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCS------------- 50
            |..:.:|.:...||.:|  :|.:...|..::  ..|:.....|:..|||.|:
Zfish     1 MRFEDLLSELNGFGRFQKMVLCINFLGRFSL--GCHFLLGNFIAAIPSHHCNISSLDVDGVFENL 63

  Fly    51 -----------RPEDYQPNSTSLLSCSVMQFDKEFKCTS------------WDFERESNYESITT 92
                       ..||..|.|..:.|..  ||......:|            |.|:..:...::.|
Zfish    64 SQEERLTVGVPAQEDGTPASCHMFSHP--QFQLLINSSSSSDLPVVECQNGWHFDNSTFISTLAT 126

  Fly    93 ELEWVCDDAYKLAVGQ---SFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGS 154
            :.:.|||   |.|:|:   :.||:|...|:..||.|:...||.|..::|.:.|......:....|
Zfish   127 QWDLVCD---KRALGKLTTTIFFLGVMFGAAAFGSLSAMFGRKPMLLVSYILGMGFGLCSVLSSS 188

  Fly   155 LPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWR 219
            |..|:..||.||..:....::..:|..|::|.:||.. :.:|..:.:..|.|..|.||.::.:||
Zfish   189 LVMFAVLRFFSGFTITGSVIISTVLNVEWVSIEHRKL-VGVIDSLAWTFGFMGFPVIAYFIRDWR 252

  Fly   220 NYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFN-GRQVDDSVFDEFIKHYR 283
            ....|.|||.:..::...::.|||.||:..||.:||...|:..|..| .::|...:..|.:.
Zfish   253 WLTVAISLPNVISIITWWWVPESARWLIVNGKADKAHYYLKKCAAMNHKKEVTARIKPEDLS--- 314

  Fly   284 EKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIK-SMIITIAFDILSRNVEGVGISPFKLFSYSGF 347
            :.:...:.....:::.::|||::|:.:::..|. ..:.|:|:.| |.|:.|.|::.:......|.
Zfish   315 KIIVTDRGSRKYSYLDLVRTPKMRRLSLLTGITWFSVATVAYGI-SFNITGFGLNMYLTQFVYGA 378

  Fly   348 CYLPAGLTIILFQNKIGRKGMACAS-LFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAV 411
            ..:||...|....:|.||......| ||||      ..:::....|.:.:|:...:..||:..:.
Zfish   379 IEIPAKFCIYYLLDKFGRHVTQAGSLLFVG------ISFIINIFIPKEKTVIRTVIAVLGKGCSA 437

  Fly   412 VAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPL-----------PSLM 465
            .::.....|.:|:.||.|:..|:.           ::|:|...|....||           ..::
Zfish   438 TSFGTVILYTSELYPTVVRQNGMG-----------YTSFIARFGVSVAPLILLSNDVWSYFSQVI 491

  Fly   466 ISFILLIGACLCLALPETLHKNLPQNLEEGEMFAK 500
            :.|:.|..|.:...||||..|.||:.:::.|...|
Zfish   492 LCFLALSAAFVAYQLPETSGKCLPETIDDIEGIRK 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	126/533 (24%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	92/385 (24%)
slc22a7b.2	XP_001337343.1	2A0119	12..517	CDD:273328	127/533 (24%)
slc22a7b.2	XP_001337343.1	MFS	140..504	CDD:119392	92/385 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588998
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950