Protein Alignment CG7342 and SLC22A13

DIOPT Version :9

• Sequence 1: NP_001247196.1
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 140/537 - (26%)
• Similarity: 243/537 - (45%)
• Gaps: 61/537 - (11%)

  Fly     1 MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC--------------A 51
            |.:..::|.:.|||.|.|:.:|:|.||:|.||..::::...:.....:.|              |
Human     1 MAQFVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAA 65

  Fly    52 DGLPASIESPVDSS-----CL-----PLNRNISTPNTCYSYNYE----LYMGYQ-------SFPS 95
            :.|..|:  |:|::     ||     |.|.::   ....|:.:.    ..||::       |..:
Human    66 EQLVLSV--PLDTAGHPEPCLMFRPPPANASL---QDILSHRFNETQPCDMGWEYPENRLPSLKN 125

  Fly    96 EMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTL 160
            |.:.||.........||:|..|.:||:::.|.|.|.:||...::...|:.....|.|.:..:..|
Human   126 EFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAFVPSFEL 190

  Fly   161 FCMFRMISGIATDSNFVMMYILVMEYMRPSVRT--LGLSICIGFFYCLGSMAAPWIAVLMRSWRG 223
            :...|.....|..........|:.|::.||.||  :.|:.|   .:.||.|....:|...|:||.
Human   191 YMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQC---NFSLGQMVLAGLAYGFRNWRL 252

  Fly   224 FLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCS 288
            ..:|.:.|.|::.|::..:|||.:||:::.:.|.|:..:::.|.:|.|.:......:.:.|
Human   253 LQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPELMNQLVPE---- 313

  Fly   289 QQNQKASP--HLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAIL 351
                |..|  :.||||:.|:||:.|||:|....|.:|.|..:|..|...|:..::...:.....:
Human   314 ----KTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGLDVYLTQLIFGAVEV 374

  Fly   352 PACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAY 416
            ||....|.:..|.|||.....:|:|.|:...:   |||..:......|:   |:|||:.....|:
Human   375 PARCSSIFMMQRFGRKWSQLGTLVLGGLMCII---IIFIPADLPVVVTM---LAVVGKMATAAAF 433

  Fly   417 NSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLL 481
            .....|:.||.||.:|..|:..|.:........:..::......:.||.:|.|.|.::...||.|
Human   434 TISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCTL 498

  Fly   482 LPETLHRTLPTSLEDGE 498
            ||||..:.|..:|:|.|
Human   499 LPETHGQGLKDTLQDLE 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	134/517 (26%)
		MFS	93..>243	CDD:119392	39/151 (26%)
SLC22A13	NP_004247.2	2A0119	12..510	CDD:273328	135/519 (26%)
		MFS	139..500	CDD:119392	101/377 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153610
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950