DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7342 and PHO84

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_013583.1	Gene:	PHO84 / 854916	SGDID:	S000004592	Length:	587	Species:	Saccharomyces cerevisiae

Alignment Length:	517	Identity:	109/517 - (21%)
Similarity:	176/517 - (34%)	Gaps:	158/517 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 TCYSYNYELYMGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGR-------L 135
            |..||.|  :.|....||:           ||.:....||:|:|....|.|||:|||       |
Yeast    88 TMMSYVY--WHGSMPGPSQ-----------TLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMEL 139

  Fly   136 PILIVANLIAMTGNLLTIWSTN-VTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSIC 199
            .|:||..::..|  :....:.| |.:...:|::.||....::.:..|:..|:.....|    ...
Yeast   140 IIMIVCTILQTT--VAHSPAINFVAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWR----GAI 198

  Fly   200 IGFFY---CLGSMAAPWIAVLM--------------------------RSWRGFL-LTTSLPLLV 234
            :|..:   ..|.::...||:::                          :.||..: |.|.|.|..
Yeast   199 MGAVFANQAWGQISGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLAC 263

  Fly   235 VPFFYLIVPESIQWLIS-KQKYDSAVVCLKRVAK------------ING------------RHVE 274
            : :|.|.:|||.::.:. ..|.:.|....::..:            |||            .|..
Yeast   264 L-YFRLTIPESPRYQLDVNAKLELAAAAQEQDGEKKIHDTSDEDMAINGLERASTAVESLDNHPP 327

  Fly   275 ESAYAEFIEECKCSQQNQ-KASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGIS 338
            ::::.:|     |....| |....||....:    ..||.:.|..:.:.   .||.....|...|
Yeast   328 KASFKDF-----CRHFGQWKYGKILLGTAGS----WFTLDVAFYGLSLN---SAVILQTIGYAGS 380

  Fly   339 PFVMFSLSATAI----------LPACLLIIALQDRIGRKAMASASLLLSGIFISVTG-------- 385
            ..|...|..||:          ||...:.:...|.||||.:..|..::......|.|
Yeast   381 KNVYKKLYDTAVGNLILICAGSLPGYWVSVFTVDIIGRKPIQLAGFIILTALFCVIGFAYHKLGD 445

  Fly   386 -GII-------FAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVR--GQGVAAVH 440
             |::       |..:....|||.:|                    ..|..||..|  ..|::|
Yeast   446 HGLLALYVICQFFQNFGPNTTTFIV--------------------PGECFPTRYRSTAHGISA-- 488

  Fly   441 VAGYAFTFFSAYILFT----------RSVFSPLPEI--ILGVLSLLGACLCLLLPETLHRTL 490
            .:|......:...|.|          :.....||.:  |..:..|||....||:|||..:||
Yeast   489 ASGKVGAIIAQTALGTLIDHNCARDGKPTNCWLPHVMEIFALFMLLGIFTTLLIPETKRKTL 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	109/517 (21%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	40/187 (21%)
PHO84	NP_013583.1	2A0109	49..554	CDD:129965	109/517 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344948
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
TreeFam	0	0.000	Not matched by this tool.
	3	2.840