DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and OCT1

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_565059.2	Gene:	OCT1 / 843656	AraportID:	AT1G73220	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	129/524 - (24%)
Similarity:	227/524 - (43%)	Gaps:	59/524 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEK-CGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCADGLPASIESPVDSS 65
            |.||:::|: .|.....|::..||..:..:..|    ..|:||..     :|..||       :.
plant    43 LTVDEVIEQHIGALGFAQILHALLVSIAWIFDA----QTTLISIF-----SDAQPA-------AR 91

  Fly    66 CLPLNRNISTPNTC--YSYNYELYMGYQS--FPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLG 126
            .|.....:...:.|  .|..:| ::|.:|  ..||.:.:|...:.:.:..::||:||:.||.|.|
plant    92 LLATGAIVEGASLCGLASGEWE-WIGPKSDTVVSEWNLICQHKFLVAVPSTLFFIGSLFGSGVYG 155

  Fly   127 YLADV-VGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYM--- 187
            ||||. .||...|:::.::.........:|.||.::...|..:|...........:|..|.:
plant   156 YLADSWFGRKKTLLLSCVLTFVTAFAISFSPNVWVYAFLRFANGFFRSGIGSCCIVLATEIVGKK 220

  Fly   188 -RPSVRTLGLSICIGFFYCLGSMAAPWIAVLMR-SWRG-FLLTTSLPL----LVVPFFYLIVPES 245
             |..|...|.     ||:.||.::.|.:|.|.| |||. :.:.:.|||    .::||.|    ||
plant   221 WRGQVGQYGF-----FFFTLGFLSLPLMAYLERKSWRNLYRIISFLPLGYAVCLLPFAY----ES 276

  Fly   246 IQWLISKQKYDSAVVCLKRVAKINGRHV-EESAYAEFIEECKCSQQNQKASPHLLDLFQTPRLRR 309
            .:||:.|.:...|:|.||::|::||:.: .:.:..:.|.|    :.:|.:|..  ..::|....:
plant   277 PRWLLVKGRNKEAMVVLKKLARLNGKQLPADLSLVDPIPE----RDDQTSSSE--KFWKTKWAVK 335

  Fly   310 HTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASL 374
            ..:::..........|..:..|.:.|..:.::..:::|....||..:...|...:.|:.:.|.|.
plant   336 RIIMVMMAGFGSGFVYYGIQLNAENLNFNLYLTVAVNALMEFPAVFIGSFLLGVMNRRPLFSNSS 400

  Fly   375 LLSGI--FISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVA 437
            .|:|.  .:.....|.....|......|.:::..||....:.||:....|..||.||.||...|:
plant   401 YLAGFACLLCAVLSIHRVIRAISVAKWLQLAVEAVGFMASSTAYDVLYVYCVELFPTNVRNTAVS 465

  Fly   438 AVHVAGYAFTFFSAYILFTRSVFSPLPE-IILGVLSLLGACLCLLLPET----LHRTLPT--SLE 495
            .:..| :.....:|.:|......|.:.. |:.||.|:|...:.|.|.||    |:.||..  ..|
plant   466 LLRQA-FMLGASAAPLLVALGRESAMMSFIVFGVASVLSGIVSLWLRETRNAPLYETLAQQGKAE 529

  Fly   496 DGEN 499
            :.||
plant   530 EIEN 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	121/501 (24%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	45/160 (28%)
OCT1	NP_565059.2	MFS_OCT_plant	102..511	CDD:340936	104/425 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.100