Protein Alignment CG7342 and SLC22A1

DIOPT Version :9

• Sequence 1: NP_001247196.1
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_005267159.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 610
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 139/521 - (26%)
• Similarity: 222/521 - (42%)
• Gaps: 77/521 - (14%)

  Fly     1 MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCADGLPASIE-----S 60
            |..||.|||:.|:....|....|:.|:::...|........:.|.|.:.|.....|.:.     |
Human     1 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCGWS 65

  Fly    61 PVDS-------------------------------SCL-PL-----NRNISTPNTCYSYNYELYM 88
            |.:.                               ||: ||     ||:......|..
Human    66 PAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQD------- 123

  Fly    89 GY------QSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMT 147
            |:      .|..:|.:.||||:|||.|.||....|.:.||:.:||.||..||...|:...|:...
Human   124 GWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAV 188

  Fly   148 GNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYM-RPSVRTLGLSICIGFFYCLGSMAA 211
            ..:|..:|.|.....:||::.|:.:..|::..|.|:.|:: ..|.||:.:...:.|  .:|.:|.
Human   189 SGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAF--TVGLVAL 251

  Fly   212 PWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEES 276
            ..:|..:..||...|..|||..:...:|..||||.:||:|:::...|:..:..:|:.||:.....
Human   252 TGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPAD 316

  Fly   277 AYAEFIEECKCSQQNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFV 341
            .....:||    ...:|.||...|||:|||||:.|.||.:.....::.|..:..::.....:.::
Human   317 LKMLSLEE----DVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYL 377

  Fly   342 MFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSV 406
            .|..||...:|...:.:...||:||....:.|.||:|....|   :||   .|.....|.:.:..
Human   378 DFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLV---MIF---ISPDLHWLNIIIMC 436

  Fly   407 VGRFGVTVAYNSGAQYATELIPTCVRGQGV----AAVHVAGYAFTFFSAYILF-TRSVFSPLPEI 466
            |||.|:|:|.........||.||.||..||    :...:.|    ..:.:|:| .|.|:..||.|
Human   437 VGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGG----IITPFIVFRLREVWQALPLI 497

  Fly   467 I 467
            :
Human   498 L 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	133/510 (26%)
		MFS	93..>243	CDD:119392	46/150 (31%)
SLC22A1	XP_005267159.1	2A0119	12..499	CDD:273328	133/510 (26%)
		MFS	118..484	CDD:119392	109/388 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153739
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950