Protein Alignment CG7342 and Sv2a

DIOPT Version :9

• Sequence 1: NP_001247196.1
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_071313.1
• Gene: Sv2a / 64051
• MGIID: 1927139
• Length: 742
• Species: Mus musculus
• Alignment Length: 581
• Identity: 116/581 - (19%)
• Similarity: 201/581 - (34%)
• Gaps: 203/581 - (34%)

  Fly    88 MGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVA----NLIAMTG 148
            :|:....:|.|...:|:.|..|| .:.::|.:||:.:.|.|||.:||...|:::    ::.|...
Mouse   186 VGFVLPSAEKDMCLSDSNKGMLG-LIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFS 249

  Fly   149 NLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLS-ICIGFFYCLGSM--- 209
            :.:..:.|  .|||  |::||:....:..:::....|::....|...|| :|:  |:.:|.:
Mouse   250 SFVQGYGT--FLFC--RLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCM--FWMIGGVYAA 308

  Fly   210 AAPWI-------------AVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVC 261
            |..|.             |....|||.|:|..:.|.:.........|||.::.:...|:|.|.:.
Mouse   309 AMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMV 373

  Fly   262 LKRVAKINGR-----------------HVEESAYAEFIE-ECKCSQQNQKASPHLLDL------- 301
            ||:|...|.|                 |.|:    |.|| :.......|:.....|.|
Mouse   374 LKQVHDTNMRAKGHPERVFSVTHIKTIHQED----ELIEIQSDTGTWYQRWGVRALSLGGQVWGN 434

  Fly   302 ----FQTPRLRRHTLIL----------------FFKSMV-------------------------- 320
                | :|..||.||::                :|..|:
Mouse   435 FLSCF-SPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYAARTKVFPGERVEHVTFN 498

  Fly   321 ITL--------------------------------CY--DAVSRN-------------------- 331
            .||                                ||  |..|.|
Mouse   499 FTLENQIHRGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVTSSNTFFRNCTFINTVFYNTDLFE 563

  Fly   332 -----------------------VQGLGISPFVMFSLS---ATAILPACLLIIALQDRIGRKAMA 370
                                   |.|.|...::::.:|   ..|:||..::...|.|:|||..|.
Mouse   564 YKFVNSRLVNSTFLHNKEGCPLDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLRML 628

  Fly   371 SASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVA-YNSGAQYATELIPTCVRGQ 434
            :.|.:||.:       ..|..|..:..:.::..|.:.|  ||::| :|:......||.|:..|..
Mouse   629 AGSSVLSCV-------SCFFLSFGNSESAMIALLCLFG--GVSIASWNALDVLTVELYPSDKRTT 684

  Fly   435 GVAAVH-----VAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTL 490
            ....::     .|....:.|::::..|::.    |.:.......||:.|.|.||||..:.|
Mouse   685 AFGFLNALCKLAAVLGISIFTSFVGITKAA----PILFASAALALGSSLALKLPETRGQVL 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	116/581 (20%)
		MFS	93..>243	CDD:119392	40/170 (24%)
Sv2a	NP_071313.1	synapt_SV2	1..742	CDD:130366	116/581 (20%)
		Interaction with SYT1. /evidence=ECO:0000250	1..57
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..145

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910