DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7342 and slc22a16

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001020659.1	Gene:	slc22a16 / 557279	ZFINID:	ZDB-GENE-041001-166	Length:	565	Species:	Danio rerio

Alignment Length:	553	Identity:	121/553 - (21%)
Similarity:	231/553 - (41%)	Gaps:	68/553 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC------------------ 50
            |:::.::.|.|.|.|..:........:...:||.:...:...||:.|
Zfish     5 VERLFDELGHFKRFQACLYFAAIFQAISCGIHYLASVFLVETPKFLCNPPLNITDVLYKNLSFTS 69

  Fly    51 ----------ADGLPASIESPVD----SSCLPL--------------NRNISTPNTCYSYNYELY 87
                      .||......|..|    |.||..              |:::   .:|.::.|:..
Zfish    70 LADIWTHYKTGDGPVVVRTSQGDQWELSPCLKALRLDAINFQYEFFGNKSV---ESCGAFVYDHS 131

  Fly    88 MGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLT 152
            ...||..::.|.||...|...|.|..|.:|.::|:::.|..||.:||.|:|:..:|......:..
Zfish   132 EVEQSIVTDWDLVCEREWLAKLTQPTFMLGVLIGALMFGDAADRIGRRPVLMATSLCQFIFGVTV 196

  Fly   153 IWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVL 217
            .::.|..||.:.|.:....:....|::::.|.|:....||| ..|:.:...:.:|.|....:..|
Zfish   197 AFTGNYYLFVVMRFLLATVSSGYLVVVFVYVTEFTGIKVRT-WTSMHVHAAFAVGIMVVALVGYL 260

  Fly   218 MRSWRGFLLTTSLPLLVVPFFYLI--VPESIQWLISKQKYDSAVVCLKRVAKING-------RHV 273
            :|.|  ::....|.|...||....  .||:..:|::|.:|..|...|..:|.|||       ..:
Zfish   261 VRVW--WIYQIILTLSTSPFLLYCWKFPETPFYLMAKGRYKEAQELLDTMAYINGLPPTLKVSDL 323

  Fly   274 EESAYAEFIEECKCSQQNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGIS 338
            ::......:::.|.:.:.:|.. .:||:|.:.::...:...:....:.:|.|...|.....||.:
Zfish   324 QDGCDRTPLKDNKQAMEVEKRL-SMLDMFGSLKMAGRSATCWAIWFIGSLGYYVFSLGSVNLGGN 387

  Fly   339 PFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVS 403
            .::...|:....:|:.|:.....||.|||...:.:|||.|:      ..:...........|.:.
Zfish   388 QYINLFLAGAVEVPSYLIGCFAMDRFGRKKTCAPALLLGGV------ACMLIIVVPQDVEVLAIV 446

  Fly   404 LSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIIL 468
            ||:.|:|.:.:|:.....|..||.||.:|...|.:..:.....:..:.:.::...::..||::|:
Zfish   447 LSMTGKFAIAIAFGLIYLYTCELYPTIIRSLAVGSGSMMCRVGSVVAPFCVYLADIWIYLPQLIV 511

  Fly   469 GVLSLLGACLCLLLPETLHRTLPTSLEDGENFG 501
            |:|:.:...|.:.|||||...|.::||:.|..|
Zfish   512 GILAFIIGILTMFLPETLGEPLTSTLEEAEALG 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	115/533 (22%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	37/151 (25%)
slc22a16	NP_001020659.1	2A0119	13..536	CDD:273328	116/535 (22%)
slc22a16	NP_001020659.1	MFS	158..526	CDD:119392	83/377 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588810
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850