DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7342 and slc22a13b

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_017209322.1	Gene:	slc22a13b / 556601	ZFINID:	ZDB-GENE-061013-532	Length:	549	Species:	Danio rerio

Alignment Length:	552	Identity:	153/552 - (27%)
Similarity:	246/552 - (44%)	Gaps:	70/552 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQ--TIISFVPKY----WCADGLPASIE 59
            |::..:||...|:|...|..:|:..|:.|:.:|.|.:.|  |.||| |.|    |.....|...|
Zfish     1 MIDFTQILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISF-PHYCNSSWILRQAPNLTE 64

  Fly    60 S-------PVDS-----SC---LPLNRN--------ISTPNTCY-SYNYELYMGYQSFPSEMDWV 100
            .       |:||     ||   .|:..:        |:|..:|. .:.|:......:..:|.|.|
Zfish    65 EKQLNLTVPLDSKGQYESCKMFTPVEMDIEDIEHYGINTTTSCIDGWVYKAPKDSSTLITEFDLV 129

  Fly   101 CADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFR 165
            |.:.......||::..|.:||:::.|.:||..||....:::..:.....:...:|.|:.::...|
Zfish   130 CENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNIYVYIALR 194

  Fly   166 MISGIATDSNFVMMYILVMEYMRPSVRTLG--LSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTT 228
            .:.|.......:..::|..|:...:.|.|.  ||.|   |:.:|.|....:|..:|:||...|..
Zfish   195 FVVGTTISGISINTFVLGTEWCGSAKRALFTILSHC---FFAIGLMLLSGVAYGIRNWRVLQLVL 256

  Fly   229 SLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQQNQK 293
            |.|:.:...:|.|:|||.:||:::.|.|||...:.:.|:||||.|.|:...      |...:|..
Zfish   257 SAPVGLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRKVSENLLD------KMEAENTA 315

  Fly   294 ASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLII 358
            .|..::|||:...||:..||:.:...|.:|.|..||.||...|:..::...:...|..||.|...
Zfish   316 KSSTMIDLFRVGYLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIYLTQLIFGMAEFPARLSCF 380

  Fly   359 ALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYA 423
            .|..|.||:...|..|||.|     |..:|..|..: |...::..::|:|:|.:..:::....|.
Zfish   381 PLIQRFGRRICQSVVLLLGG-----TACLIIPAIPA-KYPIVVTVIAVIGKFSLAASFSIVYVYT 439

  Fly   424 TELIPTCVRGQGVA----AVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPE 484
            .||.||.||..||.    ...|||..........::..::    |.||.|.|..:|..|..||||
Zfish   440 AELYPTVVRQNGVGLNSMCARVAGILAPLIGLLDVYHHAI----PMIIYGSLPFVGGALTFLLPE 500

  Fly   485 TLHRTLPTSLEDGENFG----------KNDRW 506
            ||:    |.|:|..:..          |.:||
Zfish   501 TLN----TDLQDHTDIPADESMTVTEVKLERW 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	144/514 (28%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	37/151 (25%)
slc22a13b	XP_017209322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588880
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950