DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7342 and slc22a15.1

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_031751719.1	Gene:	slc22a15.1 / 448510	XenbaseID:	XB-GENE-959503	Length:	560	Species:	Xenopus tropicalis

Alignment Length:	526	Identity:	138/526 - (26%)
Similarity:	230/526 - (43%)	Gaps:	73/526 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEKCGDFSRLQM-IMLLLFCVINVLSALHYYSQTIISFVPKY-WCADGLPAS-IESPVD 63
            :||:..|:..|:....|: :..||..::.:.||......||:...|.| |..|.|.|: ......
Frog    27 MEVEGALKLVGEMGIYQIYLSFLLAVLLQLYSATEAIIITILGATPPYHWMNDSLTANGSRGKQY 91

  Fly    64 SSCLPLNRNISTPNTCYSYNYELYMG-YQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGY 127
            .|.||...         .:.:.::.| :.|..||...|...|:::::..|::|.|.::|.:..|.
Frog    92 GSQLPAEG---------EHGHVVFDGNFTSIVSEWFLVGGAAYEVSVSSSVYFGGVLIGVISFGQ 147

  Fly   128 LADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVR 192
            |:|..||.|:.:....:.:...::...:....||.:.|.:.|:......::.::|:.|
Frog   148 LSDRFGRKPVYVTGLALEVVFAVMNALTPIFPLFLLTRFLVGVMNGGMSLVAFVLLNE------- 205

  Fly   193 TLGLSICIGFFY--CLGSMAAPWIAV----------LMRSWRGFLLTTSLPLLVVPFFYLIVPES 245
                  |||..|  ..||:.:...||          .:||||...|..::....|....|.:|||
Frog   206 ------CIGASYWAAAGSLGSLCFAVGIAQFALIGYFIRSWRLLALLVNVQGAAVLALSLCIPES 264

  Fly   246 IQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQQNQKA-SPHLLDLFQTPRLRR 309
            .:||.::.:...|...|..:.:.|.|.|.....        |.:|...| |.::|.::....||:
Frog   265 PRWLHAQGRLREAQESLLSLGRRNRRKVTSFTL--------CPRQKDSAHSANILTIYSNAILRQ 321

  Fly   310 HTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPA---CLLIIALQDRIGRKAMAS 371
            .|||:.:...|.:|.|..::.:...||...::..:||..|.|||   |:.:|. ..|:||:..
Frog   322 RTLIMMWVWFVCSLVYYGLTLSSGDLGGDIYLNLALSGLAELPAYPLCMYLIN-HKRVGRRGS-- 383

  Fly   372 ASLLLSGIFISVTGG---IIFAASASDKTTTLLV----SLSVVGRFGVTVAYNSGAQYATELIPT 429
                |:| |:.|.||   :|........:..|.|    :||::|:..::.|:|....|::||.||
Frog   384 ----LAG-FLCVGGGACLLIMLVPGKTGSGPLSVLNSQTLSLLGKLNISAAFNIVYIYSSELYPT 443

  Fly   430 CVR--GQGVAAV--HVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTL 490
            |||  |.||.::  .:.|....|..|    .|.....||.|:.|...:....|.|||||||...|
Frog   444 CVRNLGMGVCSMFSRIGGIIAPFIPA----LRFAHWALPFIVFGAAGVSAGLLSLLLPETLSAPL 504

  Fly   491 PTSLED 496
            |.:|.|
Frog   505 PETLAD 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	131/509 (26%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	35/161 (22%)
slc22a15.1	XP_031751719.1	MFS	90..497	CDD:421695	112/448 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920