DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and Orct2

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster

Alignment Length:	538	Identity:	145/538 - (26%)
Similarity:	261/538 - (48%)	Gaps:	46/538 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCA----DG----LPA---SI 58
            |:.:...|||.|.|.|:..|.|:.::..|.|..:...:...|.:.||    :|    ||.   ::
  Fly     4 DEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNL 68

  Fly    59 ESPVDSSC---------------LPLNRNISTPNTCYSYNYELYMGYQSFPSEMDWVCADAWKLT 108
            ..|.:..|               :|  |:.:...||.||.|:......|..:|.:.||...:...
  Fly    69 SYPENERCSYYDVDYTEEYLNGSIP--RSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAA 131

  Fly   109 LGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATD 173
            ...|:|.:|.::||:|.|.|:|..||.|||..:.:|.:...:|...:.....:...|::.|..|.
  Fly   132 TSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTS 196

  Fly   174 SNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFF 238
            ..|::.|::.||.:.|..| |...|.:..|:.:|.|.....|..:..||...:..:||.|:..|:
  Fly   197 GVFLVAYVVAMEMVGPDKR-LYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMFY 260

  Fly   239 YLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQQNQKAS-------- 295
            |.|:|||.:||:.|.:.|.|:..:::.|:.|...:.:.|.:|.::|.:.|::..|..
  Fly   261 YWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDE 325

  Fly   296 ---PHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLI 357
               |.:.|||..|.|||.||::|...:|.:..|..:|.|...||.:..:.|.:|....:||.:.:
  Fly   326 GPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFL 390

  Fly   358 IALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQY 422
            :...:|.||:::....|:::|:.:..|  :|.    ..:..||:|:.:::|:..:|.:|.:...:
  Fly   391 LLTLNRWGRRSILCGCLVMAGLSLLAT--VII----PQRMHTLIVACAMLGKLAITASYGTVYIF 449

  Fly   423 ATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLH 487
            :.|..||.||...:.|..:........:.::.|..:::.|||.:|.|.|:|:...|.||||||.:
  Fly   450 SAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLLSLLLPETHN 514

  Fly   488 RTLPTSLEDGENFGKNDR 505
            :.:..::.|||.|||..:
  Fly   515 KPMLETIADGERFGKKTK 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	138/515 (27%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	42/149 (28%)
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	138/517 (27%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	102/382 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458394
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.990