DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and CG17751

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	236/529 - (44%)
Similarity:	346/529 - (65%)	Gaps:	17/529 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCA---DGLPASIESPVD 63
            :::..:|||||:|...|:::|.||...|::|:|||:|||||||.|.:.|:   |..|.| .|.:.
  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQPNS-TSLLS 64

  Fly    64 SSCLPLNRNISTPNTCYSYNYELYMGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYL 128
            .|.:..::...    |.|:::|....|:|..:|::|||.||:||.:|||.||:||.:||:..|||
  Fly    65 CSVMQFDKEFK----CTSWDFERESNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYL 125

  Fly   129 ADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRT 193
            ||.:||||..:::.|...:|:..|.:..::..|...|.|||:..|:.:|:|||||.||:.|..||
  Fly   126 ADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRT 190

  Fly   194 LGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSA 258
            .||:|.:|.|||:|.|.:||||:.:.:||.:|...|||.|.:..|.:.:.||.:||::|.|::.|
  Fly   191 FGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKA 255

  Fly   259 VVCLKRVAKINGRHVEESAYAEFIEEC--KCSQQNQKASPHLLDLFQTPRLRRHTLILFFKSMVI 321
            ...|:.|||.|||.|::|.:.|||:..  |.:....|:|...:.:.:|||||:.|:||..|||:|
  Fly   256 EKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNSQNKSSDTFMGMLRTPRLRKFTIILLIKSMII 320

  Fly   322 TLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGG 386
            |:.:|.:||||:|:|||||.:||.|....|||.|.||..|::||||.||.|||.:..|..:.||.
  Fly   321 TIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATGY 385

  Fly   387 IIFAASASDKTTTL--LVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFF 449
            ::.....||.:..|  :|||   ||:|..|||::.||||.|:|||.|:|:|||.:||.|.||.||
  Fly   386 LVATLDPSDYSVLLGFMVSL---GRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFF 447

  Fly   450 SAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGENFGKNDRWYTFSFLEG 514
            |:||::..:.:.|||.:::..:.|:||||||.||||||:.||.:||:||.|.|.::||.|.....
  Fly   448 SSYIIYLGTFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSR 512

  Fly   515 R--TQSAAT 521
            |  ||.:||
  Fly   513 RPKTQKSAT 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	216/485 (45%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	67/149 (45%)
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	217/486 (45%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	170/374 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471388
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.860