DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and CG7333

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster

Alignment Length:	540	Identity:	225/540 - (41%)
Similarity:	340/540 - (62%)	Gaps:	22/540 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC---------ADGLPAS 57
            ::..::|:|||::.|.|:::|||:...|:|.:|||:|||:|:|.|::||         .:|:.:.
  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSV 65

  Fly    58 IESPVDSSCLPL------NRNISTPNTCYSYNYELYMGYQSFPSEMDWVCADAWKLTLGQSMFFV 116
            .|:...|||.||      ...:||...|.::.:....||:|..:|:.|||..:....:|||.||:
  Fly    66 YENISASSCTPLLGVVNGTGVVSTNRKCRNWIFNRESGYESITTELKWVCDKSHHPAVGQSFFFM 130

  Fly   117 GSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYI 181
            |||||:::.|||:|.|||||.|::|.|...||:.:|.:...:..|...|.:||::||:.:.:|||
  Fly   131 GSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYI 195

  Fly   182 LVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESI 246
            ||.||:.|..||.||:|.:..|||.|.|.:||.|:.:.:||.:|...|||.|.|..:..::.||.
  Fly   196 LVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESA 260

  Fly   247 QWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQ-QNQKASPH---LLDLFQTPRL 307
            |||::|:|||.||:|||:|||.|.||||||.:.||::..:..: |:.|.:.|   .|.:|.||||
  Fly   261 QWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERELQDYKLNSHEDTFLAMFLTPRL 325

  Fly   308 RRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASA 372
            ||.||.|..||::|||..|.::||::|||.|||.:||.::...|||.:.|:.||::||||.||..
  Fly   326 RRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACT 390

  Fly   373 SLLLSGIFISVTGGIIFAASASDKTTTLLVSLSV-VGRFGVTVAYNSGAQYATELIPTCVRGQGV 436
            :|.:.|:..:.||.:|  |........||:::.| :||||.||:|::..|||.|:|||.||||.|
  Fly   391 ALFVGGLITTATGFMI--AHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAV 453

  Fly   437 AAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGENFG 501
            :.:||.|.|.:..:.|:::....:.|||.|.:..|...||.|||.|||||::.||.:|.|||.|.
  Fly   454 SNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFA 518

  Fly   502 KNDRWYTFSFLEGRTQSAAT 521
            .|:.:..|.....:.::..|
  Fly   519 LNESFLYFPCFSRKEKNVRT 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	212/498 (43%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	64/149 (43%)
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	214/500 (43%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	169/374 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471393
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	9	8.860