DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and CG6126

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	584	Identity:	159/584 - (27%)
Similarity:	265/584 - (45%)	Gaps:	84/584 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILE----KCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC----ADGLPASI 58
            :.||.:||    |.|:|.:.|.:...|..:..:.:.:|..|...::.||::.|    .|....|:
  Fly     1 MAVDYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSV 65

  Fly    59 ESPVDSS----CLPLNRN----------ISTPNTCYSYNYELYM---GYQSFPSEMDW--VCADA 104
             :|.:||    .:||..|          .|:|.|..:.|.|.|:   .|......:||  ||...
  Fly    66 -TPWNSSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRR 129

  Fly   105 WKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISG 169
            |...:.|::|.:|...|::.||.|||.|||..:...:.|..:...:...:......|.:.|.:.|
  Fly   130 WMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLG 194

  Fly   170 IATDSN-FVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSM-AAPWIAVLM-RSWRGFLLTTSLP 231
            |...:. ::..::|.||.:.|:.||: ..|.....:..|.| .|.|.|::. |.|...:......
  Fly   195 IVGSAGAYICGFVLTMELVGPTKRTV-CGITFQAVFAGGIMLVAGWGALIPDRQWLQVIYGLHGC 258

  Fly   232 LLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGR--HVEESAYAEFIEECKCSQQ---N 291
            |.:..:::|  .||.:||..:.:...||..:.:..:|||.  .|::..|.:     |..||   .
  Fly   259 LFLGHWWWL--DESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQ-----KAKQQAAAE 316

  Fly   292 QKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGIS-------PFVMFSLSATA 349
            :|:|..|.|||:||.||       .|::.:.||:.|.|....||.:|       |:::..:....
  Fly   317 EKSSAGLSDLFRTPNLR-------MKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLV 374

  Fly   350 ILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTV 414
            ..|:.:.|:.:.||:||:::.| :|:|.|....:....|...|.:.....:...|.:.|.|  .|
  Fly   375 EFPSYITIVFVLDRLGRRSITS-TLMLGGGLCCIVAAYIAQGSTTSTAVVMAGKLLIAGSF--AV 436

  Fly   415 AYNSGAQYATELIPTCVR----GQGVAAVHVAGYAFTFFSAYILFTRSVFSP-LPEIILGVLSLL 474
            .||    |:.||.||.||    |.|.....::| |.|    .::.....|.| :|.::.||::|:
  Fly   437 IYN----YSAELFPTVVRNSAMGLGSMCARLSG-ALT----PLITLLDSFDPKIPAVLFGVVALI 492

  Fly   475 GACLCLLLPETLHRTLPTSLEDGENFGKNDRWYTFSFLEGRTQSAATLDTQNAKMYSQSTESAV 538
            .....:.||||:::.:|.|:||||||||.|.|:        :|.|.....||: :|....|..|
  Fly   493 SGFWVMFLPETMNQPMPESIEDGENFGKGDTWF--------SQCAGRKKRQNS-VYPDDPEQMV 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	135/521 (26%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	38/154 (25%)
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	135/522 (26%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	103/397 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	5.060