DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and CG14857

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster

Alignment Length:	564	Identity:	208/564 - (36%)
Similarity:	342/564 - (60%)	Gaps:	31/564 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC-ADGLP-------ASI 58
            ::.|:||||||...|.|.:|:||...|...:.:|||||.||.|||::|| .:.|.       |:|
  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEEIAAI 65

  Fly    59 ESPV--DSSCLPLNR----NISTPN-TC--YSYNYELYMGYQSFPSEMDWVCADAWKLTLGQSMF 114
            .:|.  ::||..|::    .::..| ||  :.|||:  .|::|..:|::|||.||:|..:|||:|
  Fly    66 YAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYD--FGFRSMNAELNWVCNDAYKARIGQSLF 128

  Fly   115 FVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMM 179
            |:||::|:...|.|.|.:||:..:|:||.....|:.||.:::|:..|.:||.|||:|..:|:.:|
  Fly   129 FLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLM 193

  Fly   180 YILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPE 244
            :|||:||:.|.:|.:.:|..:|..:|||::.|||::||..:||.:|..::|..|||..||.:|.|
  Fly   194 FILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFVVQE 258

  Fly   245 SIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEEC----KCSQQNQKASPHLLDLFQTP 305
            |.||||::...:.|:..||.:|..||..|:.:.:..|...|    |.|.|.::.: .:.||.:||
  Fly   259 SAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLSNQPEQTA-GIFDLLRTP 322

  Fly   306 RLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMA 370
            .||:.:|::.|..|:.:|.::.:||||:|:|:||||:|||.|..:.|:..:...||.|:||||.|
  Fly   323 NLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATA 387

  Fly   371 SASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQG 435
            ..::|.:|: :|...|:..:...:.|..|||::.::..|.|:::.|...:|:|:||:|||||.:|
  Fly   388 FLAMLCTGL-LSCALGVALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRG 451

  Fly   436 VAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGENF 500
            :||||:|....:|.|.|::...:..:..|.:||.:|.|..:...|:||||.:|.||.:|.|||.|
  Fly   452 IAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAF 516

  Fly   501 GKNDRWYTFSFLEGRTQSAATLDTQNAKMY------SQSTESAV 538
            ||.:...:|..........:...|:..:::      ...||:.|
  Fly   517 GKGESMLSFDCWRRHDDDVSKEATEEVRLHQLNGQTKSETEAEV 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	188/499 (38%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	62/149 (42%)
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	190/501 (38%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	134/345 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471365
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	9	8.910