DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7342 and slc22a6l

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_996960.2	Gene:	slc22a6l / 404609	ZFINID:	ZDB-GENE-040426-2249	Length:	560	Species:	Danio rerio

Alignment Length:	537	Identity:	142/537 - (26%)
Similarity:	241/537 - (44%)	Gaps:	53/537 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCADGLPASIES----PVDSSCL 67
            :||:.|...|.|::.:.|..:..::.|.|...|..::.||.:.|......|:.|    .|..:.:
Zfish     6 LLEQVGSTGRFQVLHVTLLSMPILMMASHNLLQNFVAAVPPHHCQPHANLSMSSTDAMDVLRATV 70

  Fly    68 PLNRN--------ISTP-------NTCYS-----------------YNYELYMGYQSFPSEMDWV 100
            ||..|        .:||       ||..|                 :.|.:.....:..:|.|.|
Zfish    71 PLGLNGKLERCKRYTTPQWQILSLNTSESLWDESMAETETQSCEDGWFYNMTEMSSTIITEWDLV 135

  Fly   101 CADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFR 165
            |.......:.|:.:..|.:||::|.|.|:|..||..:|:::||:...|.....:||:.|:||:||
Zfish   136 CDYRALKQMSQTTYMGGVLVGAIVFGGLSDRFGRRVLLLISNLMMAIGGTCVAFSTSFTMFCVFR 200

  Fly   166 MISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSL 230
            :..|:|.....:..:.|::|::...|||: :....|:.|..|.:....:|..:|.||...|..||
Zfish   201 VCCGMALSGLVLNSFSLIVEWIPTRVRTV-VGTGTGYCYTTGQLILAAVAYCIRDWRWLTLAVSL 264

  Fly   231 PLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVE------ESAYAEFIEECKCSQ 289
            |..|...:.....||.:||:..:|.:.||..||.||:||||..|      |.......:|..||
Zfish   265 PFYVSFLYSWWFLESARWLVLTKKPEQAVKNLKTVARINGRSAEGDKIDLEMLQESMKKEMACS- 328

  Fly   290 QNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPAC 354
               |.|...|||.:|..:|..|:.|.......:..|..:|.::|..|:|.:::..:.....:||.
Zfish   329 ---KGSYSALDLLRTSTMRTITICLSAVWFSTSFAYYGLSMDLQKFGVSIYLIQIIFGAVDIPAK 390

  Fly   355 LLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSG 419
            :::......:||:.....:|:|:||.|     :|.....|| ...|..||:|:|:..:..::|..
Zfish   391 IIVTICMSMLGRRPSQCGALVLAGIMI-----LINLLVPSD-LQMLRTSLAVIGKGCLAASFNCC 449

  Fly   420 AQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPE 484
            ..||.||.||.:|..|:..|.:........:..:|.....:..:|..|.|...::.......|||
Zfish   450 YLYAGELYPTVIRQSGMGWVSMMARFGAMVAPMVLLLGDDYPWIPGFIYGGAPIVSGIFAFFLPE 514

  Fly   485 TLHRTLPTSLEDGENFG 501
            ||.:.||.:::|.::.|
Zfish   515 TLSQPLPDTIQDIDDRG 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	136/520 (26%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	44/149 (30%)
slc22a6l	NP_996960.2	2A0119	11..523	CDD:273328	138/522 (26%)
slc22a6l	NP_996960.2	MFS	116..513	CDD:119392	110/407 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589035
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950