DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7342 and slc22a7b.1

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021322800.1	Gene:	slc22a7b.1 / 393320	ZFINID:	ZDB-GENE-040426-1311	Length:	560	Species:	Danio rerio

Alignment Length:	567	Identity:	132/567 - (23%)
Similarity:	255/567 - (44%)	Gaps:	73/567 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC------ADGLPASIES 60
            ::.|.||::...|.|.|:.:::|..:..:....|:.....|:.:|.:.|      ||||....:.
Zfish    11 MKFDNILDETDGFGRYQIALVMLLFIPRITIPCHFLLNNFIAAIPSHHCDISSLDADGLGNLTQK 75

  Fly    61 PVDSSCLPLNRNISTPNTCYSY---NYELYMGYQS-----------------------FPSEMDW 99
            ......:|...: .||.:|:.:   .::|.:...|                       ..::.|.
Zfish    76 ERLIVSVPAQED-GTPASCHMFAHPQFQLLINSSSSSALPVVECQNGWHFDNSTFISTLATQFDL 139

  Fly   100 VCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMF 164
            ||..........::||||.:.|::..|.|.|..||..:|:|:.:.::..::.:.:|::..:|..|
Zfish   140 VCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSVTSAFSSSYIMFAAF 204

  Fly   165 RMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFF----YCLGSMAAPWIAVLMRSWRGFL 225
            |.::|:|......:..:|.:|::....||.     :|.|    :.:|:|.....|.::..||..:
Zfish   205 RFLTGLALTGISNISVVLSIEWVDTKHRTF-----MGLFGSMSWSIGNMLLAGFAFMVTDWRLLI 264

  Fly   226 LTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECK---- 286
            :..:.||.:....:..:|:|.:|||:..|.::|...|.:.|..|.|       .:|....|
Zfish   265 VIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNQR-------LDFTSRVKPETL 322

  Fly   287 ---CSQQNQKASPHLLDLFQTPRLRRHTLILFFKSMV---ITLCYDAVSRNVQGLGISPFVMFSL 345
               .:..::..|...|||.:||:||:.||   |..:|   :...|..:|.|:.|.|:.|::...:
Zfish   323 STVVTVDHRGHSYTYLDLVKTPQLRKLTL---FTGIVWYGVASTYYGISLNITGFGLDPYLTHFI 384

  Fly   346 SATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRF 410
            .|...:||.:|:....:::||:...:.:|:|:|..|.:  .||    ...:..|....::|:|:.
Zfish   385 YAAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILI--NII----TPTEYWTFRTVIAVLGKG 443

  Fly   411 GVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLG 475
            ....::.:...|.|||.||.:|..|:...:.........|..|:....::..|||:|...:::..
Zfish   444 LSEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWKLLPEVIFCSMAIFC 508

  Fly   476 ACLCLLLPETLHRTLPTSLEDGENFGKNDRWYTFSFLEGRTQSAATL 522
            ..:.||||||.:.:||.::||.|:..|...::|.:     .|||..|
Zfish   509 GIIALLLPETNNASLPETVEDIEDMRKKPVYFTTA-----DQSAMPL 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	118/524 (23%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	34/153 (22%)
slc22a7b.1	XP_021322800.1	Sugar_tr	22..526	CDD:331684	120/525 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588970
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950