DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and Slc22a12

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_038941497.1	Gene:	Slc22a12 / 365398	RGDID:	621628	Length:	578	Species:	Rattus norvegicus

Alignment Length:	575	Identity:	134/575 - (23%)
Similarity:	240/575 - (41%)	Gaps:	109/575 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTII----SFVPKYWCADGLPASIESPVDSSC 66
            ::|::.|...|.|    ||..|..|...|...:|.::    :.||.:.|...|   :::....:.
  Rat     5 ELLDRVGGRGRFQ----LLQAVALVTPILWVTTQNMLENFSAAVPHHRCWVPL---LDNSTSQAS 62

  Fly    67 LP--LNRNI-----------STPNTCYSYNYELYMGYQSFPSEMDW------VCADAWKL----- 107
            :|  ..|::           ..|:.|..:....:...:|..:..:|      .|.|.|..
  Rat    63 IPGDFGRDVLLAVSIPPGPDQRPHQCLRFRQPQWQLIESNTTATNWSDADTEPCEDGWVYDHSTF 127

  Fly   108 ------------------TLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVAN-LIAMTGNLLTI 153
                              .:.||:|..|.:||:.|.|:.:|..||..:|..:. |::::|.:..:
  Rat   128 RSTIVTTWDLVCDSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTIAAL 192

  Fly   154 WSTNVTLFCMFRM-----ISGIATDSNFVMMY--------------------ILVMEYMRPSVRT 193
            ..| ..|:|:||.     ::|:..::..:.|:                    :.|||:.......
  Rat   193 MPT-FPLYCLFRFLVASAVAGVMMNTASLCMFPVVLGREGYMQDPELTPSLLLAVMEWTSAQAGP 256

  Fly   194 LGLSI-CIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDS 257
            |.::: .:||.:  |.:....:|..:||||...|..|.|..:...:...:|||.:|||:..:.|.
  Rat   257 LMMTLNALGFSF--GQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGRLDQ 319

  Fly   258 AVVCLKRVAKINGRHVEESAYAEFIEECKCSQQNQ----KASPHLLDLFQTPRLRRHTLILFFKS 318
            ::..|:|||.:|.|..|.....  :|..:.:.|.:    :|...|..|..||.||..|.|    |
  Rat   320 SLRELQRVAAVNRRKAEADTLT--VEVLRSAMQEEPNGNQAGARLGTLLHTPGLRLRTFI----S 378

  Fly   319 MVITLCYDA-------VSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLL 376
            |   ||:.|       ::.::|.||.:.|::.:|.....||..:..:.|..|:||:...::||:|
  Rat   379 M---LCWFAFGFTFYGLALDLQALGSNIFLLQALIGIVDLPVKMGSLLLLSRLGRRLCQASSLVL 440

  Fly   377 SGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHV 441
            .|  :.:...|:......    .|..||:|:|...:..|:.....:::||.||.:|...|....|
  Rat   441 PG--LCILANILVPREMG----ILRSSLAVLGLGSLGAAFTCVTIFSSELFPTVIRMTAVGLGQV 499

  Fly   442 AGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLED 496
            |..........:.......|.||.::.||:.:|.....||||||.:..||.:::|
  Rat   500 AARGGAMLGPLVRLLGVYGSWLPLLVYGVVPVLSGLAALLLPETKNLPLPDTIQD 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	130/562 (23%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	40/205 (20%)
Slc22a12	XP_038941497.1	MFS_OAT	109..541	CDD:340932	107/449 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346839
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950