DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and CG4630

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster

Alignment Length:	589	Identity:	146/589 - (24%)
Similarity:	250/589 - (42%)	Gaps:	105/589 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKY----------------- 48
            :|:.|.||.:.|:|.|.|....||.|:..:.:|.:..|....:..|.|
  Fly    12 VLDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGA 76

  Fly    49 -WCADGLPAS---------------------IESPVDS-SCLPLNRNISTPNTCYSYNY------ 84
             |.:..:|.|                     :||..|. |..||::       |::.|:
  Fly    77 NWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQ-------CFAENFTTETER 134

  Fly    85 --ELYMGYQSFPSEMDW--VCAD-AWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPI-LIVANL 143
              :...|.........|  .|.: .|||....::.|.|.|||:.:.|||||..||..| |.....
  Fly   135 CNQFVYGSSERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVF 199

  Fly   144 IAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGS 208
            :|:|| :....|.:...|..|.:::.:.|...:.:.:|:.:|.:.|..|.:. ||.:.:||.:|.
  Fly   200 MALTG-VAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMS-SIVLNYFYAVGE 262

  Fly   209 MAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHV 273
             |...::|.:..||...|..|:|.|:...::.:||||::||:::.:.:.|.|.::|.||:|.|.:
  Fly   263 -ALLGLSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDI 326

  Fly   274 EESAYAEFIEECKCSQQNQK----------------------ASPHLLDLFQTPRLRRHTLILFF 316
            .....|.|.::...::..|:                      |..|:|       :.|:.::|..
  Fly   327 SVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHIL-------MGRYAILLLI 384

  Fly   317 KSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFI 381
            .: |..:.|..:|.|...|..:.::.|:|.....:|...|......|.||:...|.||||..|..
  Fly   385 WA-VNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITC 448

  Fly   382 SVTGGIIFAASASDKTTT-------------LLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRG 433
            ..:|.:..|........|             |:|:|.:||:.|:|.::.....:..|::||.:|.
  Fly   449 VASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRS 513

  Fly   434 QGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGE 498
            .||..:..........:.::....|.:.|||.::.|.|||:...|.||||||.:|.||.::|:..
  Fly   514 GGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEAI 578

  Fly   499 NFGK 502
            ..||
  Fly   579 ALGK 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	137/565 (24%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	43/153 (28%)
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	139/567 (25%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	96/385 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458515
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.990