DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and B0361.11

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001021124.2	Gene:	B0361.11 / 3565709	WormBaseID:	WBGene00015165	Length:	578	Species:	Caenorhabditis elegans

Alignment Length:	525	Identity:	125/525 - (23%)
Similarity:	220/525 - (41%)	Gaps:	70/525 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQT--IISFVPKYWCADGLPASIESPVDS 64
            |:.||.:|..|.:.:.|:...:|...:|     .:||.:  |:|||             :..::.
Worm    34 LDPDKFVEAYGAYGKYQIFTYVLVQTLN-----FFYSSSMYIMSFV-------------QLNLEK 80

  Fly    65 SCLPLNRNISTPNTCY----------SYNYELYMGY--------------QSFPSEMDWVCADAW 105
            .|...|..|....||.          :.|.| |.|.              .:...:.|..|:..:
Worm    81 QCEYKNETIPISETCQIETESSKAFGNLNGE-YCGIAENTLVNVTNQKASTNLLVDFDLSCSHWF 144

  Fly   106 KLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGI 170
            ....|.::|.:|:|:....:..|||..||.||::...::|...|:...:|.|..:|.:.|...|.
Worm   145 FQEFGLTIFTIGAVIAVPFMSMLADRYGRKPIIVTTAILAFLANMAASFSPNFAIFLILRAFIGA 209

  Fly   171 ATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVV 235
            .:||...:..:...||:....|. .:::.....:.||.:....:.::...||......|||.:..
Worm   210 CSDSYLSVASVATCEYLSEKARA-WITVVYNVAWSLGMVWTLLVTLMTDDWRWRYFIVSLPGVYG 273

  Fly   236 PFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQQNQKASPHLLD 300
            ...:..:|||..|||:|.|.:.....:|...::|      :...|| .:|:.|..:::.......
Worm   274 FALWYFLPESPHWLITKNKTEKLKKYIKTANRVN------NVSPEF-NDCQQSSHHEEKHESFKA 331

  Fly   301 LFQTPRLRRHTLILF---FKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIALQD 362
            |..:.:|   ..:||   |..|||:|.|.|:|.....||......|..|:...:||.|.:|.|..
Worm   332 LLGSKKL---IWLLFANGFIEMVISLVYFAISFMSVELGGDQVQAFLYSSLIEIPAGLAVIPLMM 393

  Fly   363 RIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELI 427
            ::|||.:....|:..  .:::.|..:|..|...|...:||:     :...|:.|:....:|||..
Worm   394 KMGRKMIVIWCLVFQ--TLALIGVTVFLDSYEFKLVIMLVA-----KVMATIIYSVHPIWATEQF 451

  Fly   428 PTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSP--LPEIILGVLSLLGACLCLLLPETLHRTL 490
            ||.||....:.:::........|.|:  ...|.||  :|.:::.:.|.:.|.|..:|.||.::.|
Worm   452 PTSVRSLCFSLMNIPQSMGIIMSPYV--KHIVMSPNWIPFVVIALFSFISATLAFMLHETKNKKL 514

  Fly   491 PTSLE 495
            ||.:|
Worm   515 PTDIE 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	117/509 (23%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	32/149 (21%)
B0361.11	NP_001021124.2	2A0114	146..506	CDD:273326	93/379 (25%)
B0361.11	NP_001021124.2	MFS	150..506	CDD:119392	92/375 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010