Protein Alignment CG7342 and SLC22A24

DIOPT Version :9

• Sequence 1: NP_001247196.1
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001129978.2
• Gene: SLC22A24 / 283238
• HGNCID: 28542
• Length: 552
• Species: Homo sapiens
• Alignment Length: 546
• Identity: 144/546 - (26%)
• Similarity: 242/546 - (44%)
• Gaps: 56/546 - (10%)

  Fly     5 DKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC------------------- 50
            |.:|::.|...|.|:.::..||:.|:|...:...:...:|.|.:.|
Human     4 DVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDTVSDNDTGTLS 68

  Fly    51 ADGLPASIESPVDSSCLP-------------LNRNISTPNT-------CY-SYNYELYMGYQSFP 94
            .|.| ..|..|:||:..|             |:.|.:.|||       |. .:.|:......:..
Human    69 KDDL-LRISIPLDSNLRPQKCQRFIHPQWQLLHLNGTFPNTNEPDTEPCVDGWVYDRSSFLSTIV 132

  Fly    95 SEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVT 159
            :|.|.||......::.||:|..||::|.::.|:|:|.|||..|..:..|.....|....::....
Human   133 TEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTCAAFAPTFL 197

  Fly   160 LFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGF 224
            ::|:.|.::|.:|.:.....:||.:|:..|..|::.:.:.: ..|.:|.|....:|..::.|...
Human   198 VYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLL-CSYSVGQMLLGGLAFAIQDWHIL 261

  Fly   225 LLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKING-RHVEESAYAEFIEE-CKC 287
            .||.|.|::|:......:.||.:|||...:.|..:..|:|||.||| ::.||:...|.:.. .|.
Human   262 QLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTMKK 326

  Fly   288 SQQNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSL--SATAI 350
            .....:....:..||:.|:||.....|.|....||:.:..:..|:|.|| |...:|.:  .|...
Human   327 ELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAITVPFYGLILNLQHLG-SNVSLFQILCGAVTF 390

  Fly   351 LPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVA 415
            ...|:.::.| :.:||:..........|:||.|.      .....:...|.|.|:.:|...|:.|
Human   391 TARCVSLLTL-NHMGRRISQILFTFPVGLFILVN------TFLPQEMQILRVVLATLGIGSVSAA 448

  Fly   416 YNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSP-LPEIILGVLSLLGACLC 479
            .||.:.:..||:||.:|.. ||.::..........|.:|.|...:|| ||.|..||..:|...:.
Human   449 SNSASVHHNELVPTILRST-VAGINAVSGRTGAALAPLLMTLMAYSPHLPWISYGVFPILAVPVI 512

  Fly   480 LLLPETLHRTLPTSLEDGENFGKNDR 505
            ||||||....||.:::|.||..|:.|
Human   513 LLLPETRDLPLPNTIQDVENDRKDSR 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	135/523 (26%)
		MFS	93..>243	CDD:119392	38/149 (26%)
SLC22A24	NP_001129978.2	MFS_OAT	109..516	CDD:340932	109/416 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153832
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950