Protein Alignment CG7342 and Slc22a1

DIOPT Version :10

• Sequence 1: NP_650815.2
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_036829.1
• Gene: Slc22a1 / 24904
• RGDID: 3224
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 161/555 - (29%)
• Similarity: 254/555 - (45%)
• Gaps: 74/555 - (13%)

  Fly     1 MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCAD------------- 52
            |..||.:||:.|:|...|....||.|:|:...|..|.....:.|.|.::|.:
  Rat     1 MPTVDDVLEQVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPGHYCQNPGVAELSQRCGWS 65

  Fly    53 ----------GLPASIESPVDSSCL---------------PL-----NRNISTPNTC-YSYNYEL 86
                      ||..|.|:...|.|:               ||     ||:......| :.:.|:
  Rat    66 QAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLVANRSQLPLGPCEHGWVYD- 129

  Fly    87 YMGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLL 151
             ....|..:|.:.||.||||:.|.||...:|..:||:|:||:||..||...|:|..|:.....:|
  Rat   130 -TPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSVSGVL 193

  Fly   152 TIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAV 216
            |..:.:.|...:||::.|:.:..::|..|.|:.|::....|.. .:|.....:.:|.:....:|.
  Rat   194 TAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRT-TAILYQMAFTVGLVGLAGVAY 257

  Fly   217 LMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEF 281
            .:..||...|..|||..:...:|..||||.:||:|:::...||..::::|:.||:..........
  Rat   258 AIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTRAVRIMEQIAQKNGKVPPADLKMLC 322

  Fly   282 IEECKCSQQNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLS 346
            :||    ..::|.||...|||:||.||:||:||.:......:.|..:..:|...|.:.::.|..|
  Rat   323 LEE----DASEKRSPSFADLFRTPNLRKHTVILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYS 383

  Fly   347 ATAILPACLLIIALQDRIGRKAMASASLLLSG------IFISVTGGIIFAASASDKTTTLLVSLS 405
            :....||..:|:...|||||....:||.|::|      |||            ..:...|.|:|:
  Rat   384 SLVEFPAAFIILVTIDRIGRIYPIAASNLVTGAACLLMIFI------------PHELHWLNVTLA 436

  Fly   406 VVGRFGVTVAYNSGAQYATELIPTCVRGQGV---AAVHVAGYAFTFFSAYILFTRSVFSPLPEII 467
            .:||.|.|:..........||.||.:|..|:   :|:...|..||.|..:.|.  .|:..||.|:
  Rat   437 CLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLM--EVWQALPLIL 499

  Fly   468 LGVLSLLGACLCLLLPETLHRTLPTSLEDGENFGK 502
            .|||.|....:.||||||....||.::|:.||.|:
  Rat   500 FGVLGLTAGAMTLLLPETKGVALPETIEEAENLGR 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_650815.2	2A0119	12..491	CDD:273328	150/531 (28%)
Slc22a1	NP_036829.1	2A0119	12..525	CDD:273328	152/533 (29%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15245	284..288		3/3 (100%)