DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and Slc22a22

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_036015188.1	Gene:	Slc22a22 / 210463	MGIID:	2446114	Length:	587	Species:	Mus musculus

Alignment Length:	583	Identity:	133/583 - (22%)
Similarity:	234/583 - (40%)	Gaps:	106/583 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCADGLPAS--------- 57
            ::.|:||...||..|.|:.|::|..:::::.:.|...:...:.:|.:.|:..|..|
Mouse     1 MDFDEILHHVGDSGRFQICMIILLNILSLVLSPHDVLENFTAAIPAHHCSINLDNSRSEVSTDMN 65

  Fly    58 --------IESPVDSSCLP-------------LNRNISTPNT-------C---YSYNYELYM--- 88
                    :..|:..:..|             |:.||||.|:       |   ::|::.::.
Mouse    66 LTTEDLMKVSIPMGPNQKPEQCRRFRYTQWQFLDSNISTFNSTELETEPCLDGWTYDHSVFTSTI 130

  Fly    89 ----------------------------GYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVL 125
                                        |.:|.....|.||.........|:....|.:|...:.
Mouse   131 VTEGLSPPQPWDSDQYYHTKHEISPCEEGLKSSVKVWDLVCDFQSFKYYAQATSLAGHLVSCPLS 195

  Fly   126 GYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVME----Y 186
            |.::|..||.|:|:..:|..........::.|.:::|:.|.:......:..:...|||:|    .
Mouse   196 GIISDRFGRKPLLMYCSLAYGAVGTYCAFAPNFSVYCVLRFLLSAFQSTILINSLILVLEEASVQ 260

  Fly   187 MRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLI--VPESIQWL 249
            ..|::..|.     |.|..:|......:|.::..|....|..:||..:  ||.|.  ||||::||
Mouse   261 WHPTIIVLS-----GLFNSIGQGVLGGLAYVISDWHLLQLAYALPFFI--FFVLFCWVPESVRWL 318

  Fly   250 ISKQKYDSAVVCLKRVAKINGRH-VEESAYAEFIEECKCSQQNQKASP-HLLDLFQTPRLRRHTL 312
            |...|.|.|...|:|:|.|||:. :.::...|.:........|..... .:.|:|..|.:|:  :
Mouse   319 IITGKTDQAWKELQRIASINGKKGIAQNLTTEDLRSKLKKDVNSTGKLFRIKDIFINPLIRK--I 381

  Fly   313 ILFFKSMVITLCYDAVS--RNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLL 375
            :|...|::....:..|.  .:||.||.:.|:.........:|:..|.......:.|:.:.:..||
Mouse   382 VLSNSSLLFAELFSFVGLLLDVQLLGKNMFLTQIFLGAIDVPSKSLTYFTIRNVSRRPLIAFLLL 446

  Fly   376 LSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNS-GAQYATELIPTCVR----GQG 435
            .:|..|::|   ||   .|::...|...:.::|: |...|:.. ...|..||.|..:|    |..
Mouse   447 TTGSCITIT---IF---ISEEMYVLRTIIFILGK-GCFAAFTCISTTYINELSPVELRSTLNGVF 504

  Fly   436 VAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGE 498
            :|.|.:||    ..||..|.||..|..||.|:.|||.::.....|.||||.:......::|.|
Mouse   505 LAVVRLAG----VLSALTLATRKYFVYLPMILYGVLPIVATISILFLPETFNLPHTDIIKDME 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	128/564 (23%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	33/155 (21%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	105/459 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844059
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.030