Protein Alignment CG7342 and Slc22a2

DIOPT Version :10

• Sequence 1: NP_650815.2
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 553
• Identity: 155/553 - (28%)
• Similarity: 251/553 - (45%)
• Gaps: 78/553 - (14%)

  Fly     1 MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC--------------- 50
            |..||.|||..|:|...|.....|..:::......|.....:.|.|.:.|
Mouse     1 MPTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPNHHCRSPGVAELSQRCGWS 65

  Fly    51 --------ADGLPASIESPVDSSCL---------------PL-----NRNISTPNTC-YSYNYEL 86
                    ..||.::.|....|.|:               ||     ||:....:.| :.:.|:
Mouse    66 PAEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYD- 129

  Fly    87 YMGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLI-AMTGNL 150
             ....|..:|.:.|||.:|.|.|.||:..||..:|::.:|||||..||...|:|..|| |::|.|
Mouse   130 -TPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVL 193

  Fly   151 LTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSV-RTLGLSICIGFFYCLGSMAAPWI 214
            :.| |.|.....:||.:.|:.:.:.:::.|||:.|::.... ||:|  ||....:.:|.:....:
Mouse   194 MAI-SPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVG--ICYQIAFTVGLLILAGV 255

  Fly   215 AVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYA 279
            |..:.:||......:||......::..:|||.:||||:.|...|:..:|.:||.||:.|..|..:
Mouse   256 AYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSLQS 320

  Fly   280 EFIEECKCSQQNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFS 344
            ...:|    ....|.:|..|||.:||::|:|||||.:.....::.|..:..::...|.:.::.|.
Mouse   321 LTADE----DTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFF 381

  Fly   345 LSATAILPACLLIIALQDRIGRK------AMASASLLLSGIFISVTGGIIFAASASDKTTTLLVS 403
            .||....||..:||...|||||:      .|.:.:..|:.:||            .|....|.::
Mouse   382 YSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFI------------PDDLQWLKIT 434

  Fly   404 LSVVGRFGVTVAYNSGAQYATELIPTCVRGQGV---AAVHVAGYAFTFFSAYILFTRSVFSPLPE 465
            ::.:||.|:|:||........||.||.:|...|   :::...|...|.|..|.|  ..::...|.
Mouse   435 VACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRL--TDIWLEFPL 497

  Fly   466 IILGVLSLLGACLCLLLPETLHRTLPTSLEDGE 498
            ::..|:.|:...|.||||||..:.||.::||.|
Mouse   498 VVFAVVGLVAGGLVLLLPETKGKALPETIEDAE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_650815.2	2A0119	12..491	CDD:273328	144/533 (27%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	146/535 (27%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288		3/3 (100%)