DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and oct-2

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_509899.3	Gene:	oct-2 / 181325	WormBaseID:	WBGene00003843	Length:	757	Species:	Caenorhabditis elegans

Alignment Length:	581	Identity:	134/581 - (23%)
Similarity:	221/581 - (38%)	Gaps:	107/581 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCADGLPASIESPVDSSC 66
            ::.:.||:..|..|..|:|:.|:..|..|..|:...|...:.:.|.:||.  :|...|....:..
Worm   154 IDFEGILQLIGGCSYWQIIVYLIISVQQVPHAMFNLSVVYMMYQPDHWCK--IPFFNEESFSAEL 216

  Fly    67 --------LPLNRNISTP------------------------------------------NTCYS 81
                    ..||..|:.|                                          |.|..
Worm   217 GYTNYTWDQVLNSTIAFPRTFNKQRNELHHDQCHYFERDYVHIKLSPWAQVKDMNATGKINRCKE 281

  Fly    82 YNYELYMGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAM 146
            :.|:..:..::..:|.:.||.:.|........:.:|.:||..|.|:::|..||...:....::.|
Worm   282 WEYDTSVMDRTIVTEWNRVCDNNWSRAHVHMSYSLGYLVGCFVGGFISDRYGRKTAITGFGILTM 346

  Fly   147 TGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSM-A 210
            ....|..:|....:|.:.|.:.....::..:..|:|.||......|::           :||: .
Worm   347 LFGFLLTYSKEFEIFLVVRFLLAATNEAADLAAYVLCMEVTGTKYRSI-----------VGSLIQ 400

  Fly   211 APW---------IAVLMRSWRGF-LLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRV 265
            |||         ||.|.:||... |:...|.::.:...|.: |||.:|||...|...|...::..
Worm   401 APWACGYAFLALIAYLTKSWTMIHLICVLLHIISLMLLYFL-PESPRWLILNNKTKQAEKIIREA 464

  Fly   266 AKIN-GRHVEESAYAEFIEECKCSQQNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVS 329
            ...| .|...:.......|:.|..:.|:|  |....||::..||...::||...:...|.|
Worm   465 CHYNKSRLPSDLGLVRHAEKKKWMKHNEK--PSYFHLFRSSELRFRNVVLFIVWIATALVY---- 523

  Fly   330 RNVQGLGI------SP--------FVMFSLSATAI-LPACLLIIALQDRIGRKAMASASLLLSGI 379
               .|:.|      ||        |.:.:..|.|| ||..:..:.|. |:|||......|..||:
Worm   524 ---YGMVIALSDQSSPGRRVFDGNFFLNNAMAGAIELPTLVFCVFLL-RMGRKRSQMLVLFGSGL 584

  Fly   380 FISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGY 444
            |:..:..:::.     |.:||.:...::.:..:..::|....:.:||.||.||...|....:...
Worm   585 FLLTSVVMVYR-----KQSTLALIFMLLSKACIQGSFNILYIFTSELNPTVVRNSAVGISSMVAR 644

  Fly   445 AFTFFSAYILFTRSVFSPL-PEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGENFGKND 504
            .....|.||.....|..|| |..|....|||..||.||||||....||.::.|.....|.:
Worm   645 MGAGASGYIAILSDVTMPLVPMTIFACFSLLAGCLVLLLPETQGLPLPDTILDSVQMVKRN 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	128/556 (23%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	35/160 (22%)
oct-2	NP_509899.3	MFS_SLC22	281..673	CDD:340875	97/418 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163137
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840