DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and F23F12.3

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_498433.3	Gene:	F23F12.3 / 175926	WormBaseID:	WBGene00017751	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	501	Identity:	108/501 - (21%)
Similarity:	212/501 - (42%)	Gaps:	65/501 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LHYYSQTII----SFVPKYWCAD-----GLPASIESPVDSSCLPLNRNIS------TPNTCYSYN 83
            |.|..|.|.    :|.|...|.|     ..|....|.|: .|..|..|.|      .|......:
Worm    21 LFYACQLIFPIFYNFHPGLSCEDPGFNFSKPKCKLSKVE-ICTELTANCSKWHIEPAPFHSMVQD 84

  Fly    84 YELYMGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTG 148
            ::::.|.:::.|        ||..|:.    |:|::||::|.|:|.|..||.|:..|...|.:..
Worm    85 FKMFCGTKAYDS--------AWIATIQ----FIGALVGALVYGHLGDHFGRKPVSFVGISIGIIF 137

  Fly   149 NLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLG--SMAA 211
            .:.:.::.:..:|.:...|.|.:.....::.|..::|::.|..|     :.:..|:..|  .:..
Worm   138 GVASGFAPSWEVFAVLLFICGTSVACIMIVFYAYILEFIEPEQR-----VFLRTFFNWGYARLVF 197

  Fly   212 PWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKING-RHVE- 274
            ..:..:...||...:.|||..|.:....|.:|||.:|..:|.::.......|:::.::| .:||
Worm   198 TLVCFICGYWRSAAIATSLLALPILPVLLWLPESPKWYATKNRFQEMKEAEKKISWLSGISYVER 262

  Fly   275 ESAYAEFIEECKCSQQNQKASPHLLDLFQTPRLRRHTLI---LFFKSMVITLCYDAVSRNVQG-L 335
            |....|.|||     ::.|... :.|||.:..:...|::   |:|.:.|.:...|..|.|:.| .
Worm   263 EDRRTEKIEE-----KDTKVYT-IRDLFSSWPIAYSTIVVGSLWFSTSVSSFGADLNSGNLAGNF 321

  Fly   336 GISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFA---ASASDKT 397
            .:|.||..:..|.:.|...||.:.:.....::......:::...:.::...:|..   .|:....
Worm   322 YLSQFVQAAAIALSKLSIFLLDLFIPSFNRQRLHQVPQIIMIACYTTIMALMISPDSDCSSQGSR 386

  Fly   398 TTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSP 462
            ...::.::::|...:.:.:::....|.|:.||.:|..|:....:........:..:.:...::.|
Worm   387 NLAIIIINIIGTSFIELTWDACYLVAAEIFPTRIRTIGIGTCSLLARIGALLAPQMAYLSEIYPP 451

  Fly   463 LPEII---LGVLSLLGACLCLLLPETLHRTLPTSLEDGENFGKNDR 505
            :|.||   :|::|||  ..|..||:|          .|.:.|..||
Worm   452 IPYIIVCSIGIISLL--ISCFFLPDT----------KGVDLGALDR 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	104/485 (21%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	33/151 (22%)
F23F12.3	NP_498433.3	Sugar_tr	76..485	CDD:278511	91/443 (21%)
F23F12.3	NP_498433.3	MFS	97..>229	CDD:119392	32/140 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163108
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840