DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7342 and Y82E9BR.16

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001022960.1	Gene:	Y82E9BR.16 / 175300	WormBaseID:	WBGene00022348	Length:	575	Species:	Caenorhabditis elegans

Alignment Length:	576	Identity:	139/576 - (24%)
Similarity:	244/576 - (42%)	Gaps:	109/576 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC--ADGLP------------ 55
            |.:....|:..:.|.|...|.|:..::.::|..|.|..|....|.|  ...||
Worm     5 DFLFTYLGEMGKYQKIQFFLVCLPTIVVSMHALSWTFASVDTPYRCRLPSDLPEKEPYYTTLLNF 69

  Fly    56 ------ASIESPV------------DSSCLPLNRNISTPNTCYSYNYELYMGYQSFPSEMDWVCA 102
                  |....|:            |...||.|      .||:.:.::        .|::::...
Worm    70 TKCTNDADANVPISEYGKPGVTCHYDRCTLPDN------ETCHEHIFD--------HSKVEYTAV 120

  Fly   103 DAWKLTLG--------QSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVT 159
            ..|::|..        |:.::||.:.||...|.|.|.:||..:..:|.:|.:|...|...:....
Worm   121 QRWEITCDRSWIKATIQAAYYVGQMAGSTTFGMLGDRIGRKKVFFLAIVIQITCAYLIAIAPYWW 185

  Fly   160 LFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGF 224
            |:.:.|..:|.:....||:..::.||.:.|..|.|. |:..|.|:.||.:.....|:...:::..
Worm   186 LYALARAGTGFSHPGIFVIAVVIGMELVGPKYRKLA-SVITGLFFALGQIFLGIEAIYFTNYQIL 249

  Fly   225 LLTTSLP---------------------------LLVVPFFY--LIVPESIQWLISKQKYDSAVV 260
            .:..:.|                           ||...||:  .:||||.:||:|:::|..|..
Worm   250 HVVIASPALLFLSYCQKSAKNRKKIDFANFLADFLLKNRFFFSRWLVPESARWLVSQKRYKEADE 314

  Fly   261 CLKRVAKINGRHVEESAYAEFIEECKCSQQNQKASPHL----LDLFQTPRLRRHTLILFFKSMVI 321
            .|::.|.:||..:.|: :.|.:::..........:|..    .|||:||.||:.||::||...||
Worm   315 VLQKAASVNGTVLPEN-WWEQLDDSTTGGGGAPGAPTKKLTGADLFRTPELRKRTLVVFFLWPVI 378

  Fly   322 TLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGG 386
            ::.|..::.....||...:|.|..:|...:||..::..|.|||||:.     :|..|:||:  |.
Worm   379 SMVYYGMAMKANVLGGDIYVNFIFAAFVEIPALFIVYLLIDRIGRRL-----ILAGGLFIA--GA 436

  Fly   387 IIFAASASDKTTTLLVSLSVVG--RFGVTVAYNSGAQYATELIPTCVRGQGV----AAVHVAGYA 445
            .:...........|.::::.:.  :..:|..|.:...|:.||.||.:|...:    ....|...|
Worm   437 CLLVNWLMGDNVQLWMAITQMAFTKGSITGVYAAIYTYSPELFPTVIRNTAMGFCSTIARVGAIA 501

  Fly   446 FTFFSAYIL--FTRSVFSPLPEIILGVLSLLGACLCLL-LPETLHRTLPTSLEDGE 498
            .::.|.:|.  |.: ||..:|   .|.:::|.|.:.|| ||||:.:.||.|:|:.|
Worm   502 ASYISMWIAEQFGK-VFMIIP---FGCMAVLAAVMTLLFLPETMGKPLPESIEEIE 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	133/560 (24%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	38/186 (20%)
Y82E9BR.16	NP_001022960.1	MFS_SLC22	107..537	CDD:340875	108/450 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010