DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and UST4r

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	551	Identity:	141/551 - (25%)
Similarity:	243/551 - (44%)	Gaps:	68/551 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC----ADGLPAS--------- 57
            ::|.:.|...|.|::.::.....:|:...|...:...:.:|.:.|    .|.:..|
  Rat     5 ELLNQVGGLGRFQILQMVFVVFTSVIVVPHIIIENFTAAIPSHRCWVPILDNVTVSDNDSRILNQ 69

  Fly    58 -----IESPVDS-----SC----------LPLN---RNISTPNT--CY-SYNYELYMGYQSFPSE 96
                 |..|:||     .|          |.||   .:|:.|:|  |. .:.|:....:.:..:|
  Rat    70 DKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSITEPDTEPCVDGWVYDRSNFHSTTVTE 134

  Fly    97 MDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLF 161
            .:.||......::.:..|.:|:.:|.:|.|.|:|..||..||..|.|..........::.|:.::
  Rat   135 WNLVCESQALNSVTKLSFMIGAFIGGIVNGLLSDRFGRKFILKYALLQMAITETCAGFAPNLFIY 199

  Fly   162 CMFRMISGIATDSNFVMMYILVMEYMRPSVRTL--GLSICIGFFYCLGSMAAPWIAVLMRSWRGF 224
            |..|.::|::.:...|.:.:|:.|:..|...|:  .|..|.|.|   |.|....:|...::|...
  Rat   200 CSLRFLAGMSLEPITVNINLLMFEWTSPKFLTMVTVLGSCAGSF---GGMILAGLAFQFQNWHHL 261

  Fly   225 LLTTSLPLLVVPFFYLI----VPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEEC 285
            .|..|:|:    ||:||    :.||.:|||...|....:..||:||.|||  :::|.....:|..
  Rat   262 QLAMSVPI----FFFLILTRWLSESARWLIVINKPQKGLKELKKVAHING--MKKSGDNITMEVV 320

  Fly   286 KCSQQNQ----KASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGIS-PFVMFSL 345
            :.|.:.:    |..|...|||.||.||:...||.|..::..|....|:.::|.|..: ..:...:
  Rat   321 RTSMKKELEAAKMRPSPRDLFHTPILRKQIYILSFIRLLFILSGVGVAIHLQHLSNNIELLQILI 385

  Fly   346 SATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRF 410
            |.::||.:.:....| :.|||:......:.|.||      .|:.|..|..:..||...::::...
  Rat   386 SVSSILFSVIGHFVL-NHIGRRITQMVIMFLRGI------SILTAIFAPQEMETLRFIMAMMAEG 443

  Fly   411 GVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSP-LPEIILGVLSLL 474
            ...::|.:.:.:|.||:||.:|......:.:.| ...||.|.:....:.:|| ||.|..|..::|
  Rat   444 LAALSYAANSLHANELLPTTLRATARGVIGMFG-NIGFFLAPLCMMLASYSPNLPWIFYGGFAIL 507

  Fly   475 GACLCLLLPETLHRTLPTSLEDGENFGKNDR 505
            ...:.||||||.:..||....|.||..|..|
  Rat   508 SGFIVLLLPETKNNPLPDCTHDVENDWKESR 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	133/529 (25%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	40/155 (26%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	111/423 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347342
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940