DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and str-176

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001294210.1	Gene:	str-176 / 13197055	WormBaseID:	WBGene00006220	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	560	Identity:	128/560 - (22%)
Similarity:	221/560 - (39%)	Gaps:	119/560 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSA-LHYYSQTIISFVPKYWCADGLPASIESPVDS 64
            |:..:|.:....||     |.|..:|::.:|.| |..::.|..|.|..:  |...||.|
Worm    40 MMVEEKKVGSLDDF-----ITLRWYCMLVLLMAELTAFTATASSKVMVF--AGANPAVI------ 91

  Fly    65 SC--LPLN-----------RNISTPNTCYSYNYELYMGYQSFPSEMDWVCADAWKLTLGQSMFFV 116
            .|  .|||           .|:..|:..|.        ::|...|.:::|.||.|:....::...
Worm    92 GCGGTPLNGCHELAAFRNETNLCEPDLRYQ--------FKSVQVEFNYICEDAKKVKNTITVQTF 148

  Fly   117 GSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYI 181
            |.:||:.:.|.::|..||...|:::.|.....|.:|.:|.::..|.::|.::|:.|....|:..:
Worm   149 GVLVGAAIFGQVSDTFGRRKALLISTLGNGLFNWITAYSPDLFYFMVWRTLAGVFTGGVTVVQMV 213

  Fly   182 LVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESI 246
            .::|.:....|   :.|.....:....:..|::|.|.:.||...:..:...:......||:.||.
Worm   214 FMVENIPRKDR---MWIQNSITWSPNLILFPFVAWLCQDWRTMSVVIAASSIATFLACLILEESP 275

  Fly   247 QWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQQNQKASPHLLDLFQTPRLRRHT 311
            :|||.|.:.:.|...|.|:.|      .:..|.|..|:......:.:|..|..   .:.:.:::|
Worm   276 RWLIQKGRIEEARKSLIRIRK------TDKLYDETFEKQLDEVLHVEAEKHAR---SSKKAKKYT 331

  Fly   312 LILFF---KSMVITLCYDAVSRNVQGLGISPFVMFSLSAT------------AILPACLLIIALQ 361
            .|..|   |.:..:|.:      :.|:..:.|:::||...            ||:.|...||.:.
Worm   332 FIHLFCTWKMIAQSLTF------ITGITCTTFIVYSLMYNMEKLSGSLYWNLAIMGASRWIINIA 390

  Fly   362 DRI--------GRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGV------ 412
            ..|        |||.:...:::.:          :||          |:.::|...||.
Worm   391 VSIADYKLPWFGRKMINQIAMICT----------LFA----------LLMIAVYLYFGYNGQLIA 435

  Fly   413 --TVAYNSG------AQY--ATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEII 467
              |||..|.      |:|  ..||.||.||...|:||.......:.||..:.:.......:|..:
Worm   436 IGTVAAVSMCSQLFIAKYMMVNELYPTAVRNLAVSAVSTMSRIGSMFSPQLFYLSDYAEWIPYAV 500

  Fly   468 LGVLSLLG-ACLCLLLPET----LHRTLPTSLEDGENFGK 502
            |....|.. ..|.|.||||    |...||.  :....|||
Worm   501 LFSCQLYDFIVLSLFLPETKGVILENHLPP--KHKRIFGK 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	121/536 (23%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	32/149 (21%)
str-176	NP_001294210.1	2A0119	13..527	CDD:273328	123/545 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162930
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940