Protein Alignment CG7342 and SLC22A7

DIOPT Version :9

• Sequence 1: NP_001247196.1
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_011512558.1
• Gene: SLC22A7 / 10864
• HGNCID: 10971
• Length: 610
• Species: Homo sapiens
• Alignment Length: 609
• Identity: 147/609 - (24%)
• Similarity: 246/609 - (40%)
• Gaps: 137/609 - (22%)

  Fly     5 DKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCA-DGLPAS-------IESP 61
            :::||:.|.|...|:..:.|..:..||..||:.....::.||.:.|| .|.||:       :|:.
Human     4 EELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDVWLEAH 68

  Fly    62 VD-------SSCLPLNRNISTPNT--------------------C-------------------- 79
            :.       ||||......:.|||                    |
Human    69 LPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYDHSEFSSTIATESQ 133

  Fly    80 ---YSYNYELYMGYQSFPSE-----MDWVCADA-------------WKLTLG------------- 110
               |..:.|:...::..|.|     :.|..|:|             |:.:||
Human   134 VGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSWRESLGGLLSGMEWDLVCE 198

  Fly   111 --------QSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMI 167
                    .:.||.|.:||::..|||:|..||..:|:||.:..:...|.:..|.:..:|.:.|.:
Human   199 QKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTL 263

  Fly   168 SGIATDSNFVMMYILVM-------EYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFL 225
            :|.|. :.|.   |:||       |::....||:. .:....|:..|.|....:..|:|.||..|
Human   264 TGSAL-AGFT---IIVMPLGEAELEWLDVEHRTVA-GVLSSTFWTGGVMLLALVGYLIRDWRWLL 323

  Fly   226 LTTSLPLL--VVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCS 288
            |..:||..  ::..::  ||||.:||:::.....|...|...|::|||.|.|.::::.......:
Human   324 LAVTLPCAPGILSLWW--VPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAA 386

  Fly   289 QQNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPA 353
            .:.....|..||||:|||||..:|........:...|..:|.:|.|||::.:....|.....||:
Human   387 GERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPS 451

  Fly   354 CLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVS---------LSVVGR 409
            .||:.......||:...:.:||.:.:...               |.||||         |:|:|:
Human   452 KLLVYLSVRYAGRRLTQAGTLLGTALAFG---------------TRLLVSSDMKSWSTVLAVMGK 501

  Fly   410 FGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLL 474
            .....|:.:...:.:||.||.:|..|:....:.|......:........|:..||::..|.::||
Human   502 AFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALL 566

  Fly   475 GACLCLLLPETLHRTLPTSLEDGE 498
            .|...||||||....||.:::|.|
Human   567 AAGTALLLPETRQAQLPETIQDVE 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	141/593 (24%)
		MFS	93..>243	CDD:119392	46/197 (23%)
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	143/595 (24%)
		MFS	206..563	CDD:119392	98/378 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153781
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.960