DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and slc22a20p.1

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_004913725.1	Gene:	slc22a20p.1 / 100489586	XenbaseID:	XB-GENE-6463910	Length:	572	Species:	Xenopus tropicalis

Alignment Length:	558	Identity:	144/558 - (25%)
Similarity:	237/558 - (42%)	Gaps:	77/558 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWC-------------ADGLPASI 58
            :|...|...|.|:|...:..:..:....|.:.|...:.||.:.|             .|.|||.|
Frog     6 LLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFLQNFSAAVPAHRCWVPSLDNNTMGYDQDHLPAFI 70

  Fly    59 ESPVDSSCLPLNRNISTPNTCYSYNYELYMGY-------QSFPSEMDWV---------CADAWKL 107
              |:|.|..||        :|..|...|:..:       .:.|.|..||         ....|.|
Frog    71 --PMDESEKPL--------SCLRYRKALHSMWTNGTSTNHTEPCEDGWVYDKSDFSSTIVTEWDL 125

  Fly   108 T--------LGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMF 164
            .        :.||::..|.:||:::||.|:|.:||..:||.:||:.........:..|...:|.|
Frog   126 VCKLRKMRQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIGSNLVMAVCGTCAAFLPNFITYCTF 190

  Fly   165 RMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTS 229
            |.:.|||.....:....|::|:..|..||:..::....|.| |.:....:|..:|.||......|
Frog   191 RCLCGIAFSGITLNTNSLILEWTPPKGRTIMGTLFAAGFTC-GQILLAALAYGIREWRWLQFAVS 254

  Fly   230 LPLLVVPFFYL---IVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKC-SQQ 290
            .|..   ||:|   :||||.:|||.|.:...|:..|:|||.|||:..|....:|.|..... |:.
Frog   255 APFY---FFFLYSWLVPESARWLILKGRSHEALKALQRVAIINGKREEGQKLSEMILISHMQSEL 316

  Fly   291 NQKASPH-LLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPAC 354
            ||...|| |.|||:||.:|:.|:.|........:.:..:..::|..|||.|::........:||.
Frog   317 NQVKRPHSLFDLFRTPGMRKVTICLMMVWFSSGVAFYGLGMDLQNFGISIFLLQFTFGAIDMPAK 381

  Fly   355 LLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSG 419
            ::...|...:||:...:..|:|||:      .::..|........|.:.|:|.|:..:..::...
Frog   382 VVAALLMTYMGRRVTQATVLILSGV------ALLTNAFIPQGMKILRMVLAVFGKGCMAASFACA 440

  Fly   420 AQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPE 484
            ..::.||.||.:|..|:..|.:.....:..:..:|....:...||..|.|:.:::.......|.|
Frog   441 YLFSGELFPTVIRQTGMGVVAMMARVGSVVAPLVLLLWEISPILPSAIYGIAAIIAGGAATFLME 505

  Fly   485 TLHRTLPTSLEDGENFGKNDRWYTFSFLEGRTQSAATL 522
            |.::.||.|:|:               :|.|:|...||
Frog   506 TNNQQLPESVEE---------------VEARSQGKHTL 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	134/520 (26%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	45/169 (27%)
slc22a20p.1	XP_004913725.1	MFS	101..485	CDD:391944	105/393 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000