DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7342 and slc22a5

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021324939.1	Gene:	slc22a5 / 100000685	ZFINID:	ZDB-GENE-091012-1	Length:	549	Species:	Danio rerio

Alignment Length:	542	Identity:	141/542 - (26%)
Similarity:	243/542 - (44%)	Gaps:	87/542 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LEKCGDFSRLQMIMLLLFCVINVL---SALHYYSQTIISFVPKYWC-------ADGLPASIESPV 62
            |.:.|.|      .:.|||::|::   :.||......::..|.:.|       .|.|.||  :|.
Zfish    11 LGQTGPF------FIRLFCLLNLIYISTGLHGLYIVFVAASPAHRCRVDVNLTEDWLEAS--APT 67

  Fly    63 D---------SSC----LPLNRNIS----TP----------NTC---YSYNYELYMGYQSFPSEM 97
            :         |.|    |....|:|    :|          ..|   :.|:.::|  :.:..||.
Zfish    68 ETLSNGDLQVSQCWRYSLQTLTNLSGQGYSPGQINITDIPRERCEDGWVYSADVY--HSTIVSEW 130

  Fly    98 DWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPIL---IVANLIAMTGNLLTIWSTNVT 159
            |.||...|::.|..|..::|.::||:|.|.|:|..||..:|   :.|..:.|   ....:|.:..
Zfish   131 DLVCDSEWRVPLASSTLYMGYLLGSIVSGQLSDRFGRKKVLFGSLAAEALLM---FAQSFSPSWL 192

  Fly   160 LFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGF 224
            :||:.....|....|.::..::|..|.:..|:|.|..::.....||:|.|..||:|..:|.||..
Zfish   193 IFCVLYFFIGAFQISLYITAFVLGNEVLSGSLRVLFTTLGAFLHYCVGYMLLPWVAFAIRHWRTL 257

  Fly   225 L-LTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKIN----------GRHVEESAY 278
            | :.:.|.::.:|.::|| |||.:||:|:.....:...|:..|:.|          ...::|:|:
Zfish   258 LRVLSGLTVVYIPLWWLI-PESPRWLLSQGHVQESEAILRDAARKNRVPAPEVIFKQSQIKEAAF 321

  Fly   279 AEFIEECKCSQQNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMF 343
                         ||:....||:.:|..:||.|.:.....|.|.:.|..:|.|...|...||:..
Zfish   322 -------------QKSKYSALDVLRTSNIRRTTFMCLLLWMAINIGYFGLSLNTTNLSGDPFLNC 373

  Fly   344 SLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVG 408
            .|||...:||.::...|.....|:.:.||.|::.|      |.::......|:..||.::|.:.|
Zfish   374 FLSAVTEVPAYIVSTFLLKSCPRRPVLSAFLVIGG------GFLLLVQLIPDRLQTLALALEMAG 432

  Fly   409 RFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSL 473
            :||.|:::.....|..||.||.:|..|:.....|....:..:.||:|..:....||.:::|.|::
Zfish   433 KFGFTMSFTVVYIYTAELYPTVLRNLGMGMCSSAARIGSITAPYIIFLGTFNRHLPYVLMGSLTI 497

  Fly   474 LGACLCLLLPETLHRTLPTSLE 495
            ..:...|.||||..:.||.:||
Zfish   498 TASLANLFLPETFGKVLPENLE 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	136/532 (26%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	45/153 (29%)
slc22a5	XP_021324939.1	Sugar_tr	12..516	CDD:331684	137/536 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588441
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950