DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and PHO84

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_013583.1	Gene:	PHO84 / 854916	SGDID:	S000004592	Length:	587	Species:	Saccharomyces cerevisiae

Alignment Length:	531	Identity:	109/531 - (20%)
Similarity:	182/531 - (34%)	Gaps:	138/531 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 TELKWVCDKSHHPAVGQSFFFMGSVVGTII----FGYLSDQVGR-------LPSLLMATLCGAT- 161
            |.:.:|......|...|:...:.:.|||:|    ||.|:|.|||       |..:::.|:...|
Yeast    88 TMMSYVYWHGSMPGPSQTLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIVCTILQTTV 152

  Fly   162 -GDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVF-------Y 218
             .....:||..|   .|.|.:.|:.....|.|..|:..|:.:.|.|.   .|:.|||       .
Yeast   153 AHSPAINFVAVL---TFYRIVMGIGIGGDYPLSSIITSEFATTKWRG---AIMGAVFANQAWGQI 211

  Fly   219 CFGLMTSPWAAIWIGN---------------------WRRYLWLASLPALGVLIYPFLICESAQW 262
            ..|::.....|.:.|.                     ||..:.|.::..|..|.:...|.||.::
Yeast   212 SGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRY 276

  Fly   263 LLT----------------KRKYDD------AVICLKKVA---KFNRRHVEESVFDEFVKYYRER 302
            .|.                ::|..|      |:..|::.:   :....|..::.|.:|.:::.:.
Yeast   277 QLDVNAKLELAAAAQEQDGEKKIHDTSDEDMAINGLERASTAVESLDNHPPKASFKDFCRHFGQW 341

  Fly   303 ELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPF--KLF--SF 363
            :.....|.:....|              ||.|....::|:..||.:.:...|:...  ||:  :.
Yeast   342 KYGKILLGTAGSWF--------------TLDVAFYGLSLNSAVILQTIGYAGSKNVYKKLYDTAV 392

  Fly   364 TSIVYLPAG------VAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAIMV 422
            .:::.:.||      |::..: :.||||.:......:...:....||....|.......|..|..
Yeast   393 GNLILICAGSLPGYWVSVFTV-DIIGRKPIQLAGFIILTALFCVIGFAYHKLGDHGLLALYVICQ 456

  Fly   423 GLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIY----------LAQYY 477
            ....||...:   ......|..||..|    |..|.|..||..:...:..          .|:..
Yeast   457 FFQNFGPNTT---TFIVPGECFPTRYR----STAHGISAASGKVGAIIAQTALGTLIDHNCARDG 514

  Fly   478 KP----LPSI--FISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYF----PC---F 529
            ||    ||.:  ..:..|..|....|.:|||..|.|.|         :||  ||.    |.   |
Yeast   515 KPTNCWLPHVMEIFALFMLLGIFTTLLIPETKRKTLEE---------INE--LYHDEIDPATLNF 568

  Fly   530 SRKEKNVRTES 540
            ..|..::.:.|
Yeast   569 RNKNNDIESSS 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	100/492 (20%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	91/464 (20%)
PHO84	NP_013583.1	2A0109	49..554	CDD:129965	101/502 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344950
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
TreeFam	0	0.000	Not matched by this tool.
	2	1.930