DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and LOC685081

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_008764922.2	Gene:	LOC685081 / 685081	RGDID:	1583222	Length:	621	Species:	Rattus norvegicus

Alignment Length:	554	Identity:	136/554 - (24%)
Similarity:	240/554 - (43%)	Gaps:	81/554 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSVYE 67
            |:||:.:.|::|.|||.:.:|.|..|.|.:...|||..:.....|.|        ||..:::...
  Rat     4 FAQVMAEVGDFGPFQVRVTILMGIPNFLSAFFVFSQVFMVLDEAHHC--------SVSWVKNHTF 60

  Fly    68 NISAS----------------SCTPLLGVVNGTGV--VSTNRKCRNWIFNR----ESGYE----- 105
            |:||:                ||.......:...:  :.::|      ||.    :||::
  Rat    61 NLSAAEQLAVSIPNDTAGRPESCLMFRPPPDSASLEDILSHR------FNETQACDSGWDYPENR 119

  Fly   106 --SITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSF 168
              |:..|...||::.:.....||.|..|.:||.::||.:.|.:||..|:|:..|........|:|
  Rat   120 PPSLKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRASILLQVLLSGITGVATAF 184

  Fly   169 VHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIG 233
            |.:...:....|.|.::.........|||.|::.|..||..: ::....:..|||.....|..:.
  Rat   185 VPSFELYMVLCFFSAIAVAGYMMSTMILVSEWVGPSWRTRAM-VLAQSNFALGLMALAGLAYGVR 248

  Fly   234 NWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKY 298
            |||....:.:.|...::.|.:::.||.:|||::.:.::|...::|.|..|.|.:...:.::.|.
  Rat   249 NWRLLQIIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLASELLNQLVP- 312

  Fly   299 YRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSF 363
                     :........|.:|..|:||:.||.|:....:.:|.       ..|||   |::..|
  Rat   313 ---------EKTGPSGNALDLFRHPQLRKVTLILIAVWFVDSLL-------YYGLG---FQVGDF 358

  Fly   364 TSIVYL----------PAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLL 418
            ...:||          ||.::.:.:..|:|||......|.:.|::.....|:...|.....||.:
  Rat   359 GLDIYLTQVIFGVVEVPARLSSIPMMEKLGRKWSQLCTLTLAGVMCVIIIFIPGDLPTVATALAV 423

  Fly   419 AIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIYLAQYYKPLPSI 483
                 :|:|.::.::.....|.||::||.:|...:..:.:.......:...|:.|.||:|.:|.:
  Rat   424 -----VGKFASSAAFTISYVYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPML 483

  Fly   484 FISCLMFFGAG-LCLTLPETLNKKLPETLADGEK 516
            ....|. .||| ||..||||..:.|.:||.|.|:
  Rat   484 IFGSLP-IGAGLLCALLPETRGQTLKDTLQDLEQ 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	129/538 (24%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	93/383 (24%)
LOC685081	XP_008764922.2	2A0119	12..510	CDD:273328	129/538 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347213
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950