Protein Alignment CG7333 and SLC22A2

DIOPT Version :9

• Sequence 1: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_003049.2
• Gene: SLC22A2 / 6582
• HGNCID: 10966
• Length: 555
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 147/547 - (26%)
• Similarity: 238/547 - (43%)
• Gaps: 61/547 - (11%)

  Fly     6 VLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSVYENIS 70
            ||:..|.:..||..:..|....:...:..|.....:.|||:|.|....:..||:....|..|.::
Human     8 VLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELSLRCGWSPAEELN 72

  Fly    71 --------ASSCTP-------------LLGVVNGTGVVSTNRK------CRN-WIFNRESGYESI 107
                    |...:|             ....|:....:.|||.      ||: |::  |:...||
Human    73 YTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRDGWVY--ETPGSSI 135

  Fly   108 TTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTL 172
            .||...||..|....:.||...:|..:|::..||::|:.||...||...|..|....:.:...|.
Human   136 VTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTY 200

  Fly   173 PWFAFSRFMSGLSTDTMYYLMYILVFEYLSPK-SRTFGLNIILAVFYCFGLMTSPWAAIWIGNWR 236
            .|....|.:.||.:...:.:.|||:.|::..: .||.|  |...|.|..||:.....|..:.:||
Human   201 TWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVG--IFYQVAYTVGLLVLAGVAYALPHWR 263

  Fly   237 RYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRE 301
            ...:..|||....|:|.:.|.||.:||:::.|..:|:..:|.:||.|.:.:..|     ::..|.
Human   264 WLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPAS-----LQRLRL 323

  Fly   302 RELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSI 366
            .|....|||   .:||.:..||::|:.|:.|:......::....:..:|...|.:.:..|.::::
Human   324 EEETGKKLN---PSFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSAL 385

  Fly   367 VYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFGATV 431
            |..||...|:|..::|||:.....:..|.|....|:.|:     |.:...|..|:..|||.|.|:
Human   386 VEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVFI-----PGDLQWLKIIISCLGRMGITM 445

  Fly   432 SYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLA--------FYVIYLAQYYKPLPSIFISCL 488
            :|:......||:.||.:|...|   |:    .||:.        |.|..|...:..||.:....|
Human   446 AYEIVCLVNAELYPTFIRNLGV---HI----CSSMCDIGGIITPFLVYRLTNIWLELPLMVFGVL 503

  Fly   489 MFFGAGLCLTLPETLNKKLPETLADGE 515
            .....||.|.||||..|.||||:.:.|
Human   504 GLVAGGLVLLLPETKGKALPETIEEAE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	142/535 (27%)
		MFS	126..499	CDD:119392	103/381 (27%)
SLC22A2	NP_003049.2	2A0119	13..525	CDD:273328	142/535 (27%)
		MFS	124..492	CDD:119392	107/391 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153654
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950