Protein Alignment CG7333 and SLC22A23

DIOPT Version :9

• Sequence 1: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_011513103.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 710
• Species: Homo sapiens
• Alignment Length: 618
• Identity: 130/618 - (21%)
• Similarity: 222/618 - (35%)
• Gaps: 164/618 - (26%)

  Fly    14 GRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHA----DLNGLSVEGIRSVYENISASSC 74
            |.:|..::||.....:......||.:.:...|..||..|    :|.|::..|......|.::...
Human    93 GGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGVTTTGRGGDMGNWTSLPT 157

  Fly    75 TPLL--------------GVVNG----------TGVVSTNRKCRNWIFNRESG------------ 103
            ||..              |...|          .|..::|..||.|.:...:|
Human   158 TPFATAPWEAAGNRSNSSGADGGDTPPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKCCQQ 222

  Fly   104 -------YESIT----TELKW--VCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMA 155
                   :::.|    .||.|  |||.:....:.:....:|.:.|.:|.|.::|.|||.|.||.:
Human   223 QETGALPWDTDTKRWRPELNWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFS 287

  Fly   156 TLCGATGDFITSFVHT------LPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIIL 214
            .:      ||..|..|      :..|:..||..|.....:...:|.|..| |.|..:.|.:.::.
Human   288 II------FILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIE-LCPPGKRFMITMVA 345

  Fly   215 AVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKV 279
            :.....|....|..|....:|:....|...|.|.:|:|..:..||.:||:..::::.|...:...
Human   346 SFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHF 410

  Fly   280 AKFNRRHVE---ESVFDEFVKYYRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSV---- 337
            .:.||.:.|   :.|..|.     |:||.                    ||.....:||.|
Human   411 TQKNRMNPEGDIKGVIPEL-----EKELS--------------------RRPKKVCIVKVVGTRN 450

  Fly   338 ----IITLSCDVIN---------RNMEGLGTSPFKLFSFTSIVYLPAGVAIL------LLQNKIG 383
                |:.|..:.:.         |:|.|.......|.:|.:..|..|.:|::      ::...:|
Human   451 LWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLG 515

  Fly   384 RKG--------MACTALFVGGLITTATGFMIAH-----LDPTENALLLAIMVGLGRFGATVSYDA 435
            |:|        .|..:|...||: ...|....|     .|..::...:|..: :|.|.:......
Human   516 RRGGLLLFMILTALASLLQLGLL-NLIGKYSQHPDSGMSDSVKDKFSIAFSI-VGMFASHAVGSL 578

  Fly   436 EIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVI------------YLAQYYKPLPSIFISCL 488
            .:.:.|||.||.:|...      :||..:|..|.::            |...:.     ||..|.
Human   579 SVFFCAEITPTVIRCGG------LGLVLASAGFGMLTAPIIELHNQKGYFLHHI-----IFACCT 632

  Fly   489 MFFGAGLC----LTLPETLNKKLPETLADGEKF 517
            :     :|    |.|||:.::.|||.:::||.:
Human   633 L-----ICIICILLLPESRDQNLPENISNGEHY 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	127/609 (21%)
		MFS	126..499	CDD:119392	91/433 (21%)
SLC22A23	XP_011513103.1	2A0119	<243..652	CDD:273328	99/458 (22%)
		MFS	259..>388	CDD:119392	34/135 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153285
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.030