DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and Slc22a17

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001347335.1	Gene:	Slc22a17 / 59049	MGIID:	1926225	Length:	520	Species:	Mus musculus

Alignment Length:	548	Identity:	134/548 - (24%)
Similarity:	219/548 - (39%)	Gaps:	128/548 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SQTLITFTPEHWCFHADL-------------NGLSVEGIRSVYENISASSCTPLLGVVNGTGVVS 88
            |..:.|..|...|.:..|             :|:||.|..     ::||:.:   ||     |.|
Mouse     3 SDPIFTLAPPLHCHYGALPPNASGWEQPPNSSGVSVAGAA-----LAASAAS---GV-----VTS 54

  Fly    89 TNRKC------------RNWIFNRESGYESITTEL--KW--VCDKSHHPAVGQSFFFMGSVVGTI 137
            |:..|            ::|.:|   |...:||..  :|  |||......:.|..|.:|...|.:
Mouse    55 TDPSCSGFAPPDFNHCLKDWDYN---GLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYL 116

  Fly   138 IFGYLSDQVGRLPSLLMATL-----CGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILV 197
            ..||.:|:.|| ..:::.||     ||..|....|....:.    .||:.|.....:...:|::.
Mouse   117 FLGYPADRFGR-RGIVLLTLGLVGPCGVGGAAAGSSTGIMA----LRFLLGFLLAGVDLGVYLMR 176

  Fly   198 FEYLSPKSRTFGLNIILA--------VFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIY-- 252
            .|...|..|   |.:.||        .|...||      |:...:||....:.:.|.:..|.|
Mouse   177 LELCDPTQR---LRVALAGELVGVGGHFLFLGL------ALVSKDWRFLQRMITAPCILFLFYGW 232

  Fly   253 PFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERELQDYKLNSHEDTFL 317
            |.|..|||:||:.||:.::|...|:.:|:.||.|      .:.:....:..||:.     |:|
Mouse   233 PGLFLESARWLIVKRQIEEAQSVLRILAERNRPH------GQMLGEEAQEALQEL-----ENT-- 284

  Fly   318 AMFLTPRLRRFTLTLLV------KSVIITLSCDVINRNME------GLGTSP--FKLFSFTSIVY 368
              ...|....|:...|:      |:::|....:.|...:.      |.|.||  |.|.|.
Mouse   285 --CPLPATSTFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSL----- 342

  Fly   369 LPAGVAIL------LLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRF 427
            |.:|.|.|      :..::.||:|:...::.:.|:   |:..::...|...:|.:....| ||.|
Mouse   343 LASGTAALACVFLGVTVDRFGRRGILLLSMTLTGI---ASLVLLGLWDYLNDAAITTFSV-LGLF 403

  Fly   428 GATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIG-LASSSLAFYVIYLAQ----YYKPLPSIFISC 487
            .:..|.......|:|:|||:|||:.:..|..:| |...|.....:::..    .:..|.:..:.|
Mouse   404 SSQASAILSTLLASEVIPTTVRGRGLGLIMALGALGGLSCPAQRLHMGHGAFLQHVVLAACALLC 468

  Fly   488 LMFFGAGLCLTLPETLNKKLPETLADGE 515
            ::..     :.||||..|.|||.|.|||
Mouse   469 ILSI-----MLLPETKRKLLPEVLRDGE 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	129/541 (24%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	95/412 (23%)
Slc22a17	NP_001347335.1	MFS_SLC22A17	63..476	CDD:341003	105/458 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843385
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030