DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and slc22a13b

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_017209322.1	Gene:	slc22a13b / 556601	ZFINID:	ZDB-GENE-061013-532	Length:	549	Species:	Danio rerio

Alignment Length:	534	Identity:	134/534 - (25%)
Similarity:	224/534 - (41%)	Gaps:	52/534 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHA------------- 52
            :||:|:|...|.:|.||..:|:.....||..:.|.|.|.....:..|:|..:
Zfish     2 IDFTQILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEK 66

  Fly    53 DLNGLSVEGIRSVYENISASSCTPL---LGVVNGTGVVSTNRKCRNWIFNRESGYESITTELKWV 114
            .||.......:..||  |....||:   :..:...|:.:|......|::.......::.||...|
Zfish    67 QLNLTVPLDSKGQYE--SCKMFTPVEMDIEDIEHYGINTTTSCIDGWVYKAPKDSSTLITEFDLV 129

  Fly   115 CDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGR----LPSLLMATLCGATGDFITS-FVHTLPW 174
            |:...:....||.:..|.:||.::||.::|:.||    |.||.:..|.|....|..: :|:....
Zfish   130 CENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNIYVYIALR 194

  Fly   175 FAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYL 239
            |.....:||:|.:|     ::|..|:.....|.. ..|:...|:..|||.....|..|.|||...
Zfish   195 FVVGTTISGISINT-----FVLGTEWCGSAKRAL-FTILSHCFFAIGLMLLSGVAYGIRNWRVLQ 253

  Fly   240 WLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYREREL 304
            .:.|.|.....||.:::.|||:||||:.|.|.|...:.|.|:.|.|.|.|::.|:
Zfish   254 LVLSAPVGLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRKVSENLLDK---------- 308

  Fly   305 QDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSIVY- 368
            .:.:..:...|.:.:|....||:..|.:.....:.:|....::.|:...|...:    .|.:::
Zfish   309 MEAENTAKSSTMIDLFRVGYLRKRALIMCYMWFVTSLVYYGVSLNVGNFGLDIY----LTQLIFG 369

  Fly   369 ---LPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFGAT 430
               .||.::...|..:.||:......|.:||     |..:|....|.:..:::.::..:|:|...
Zfish   370 MAEFPARLSCFPLIQRFGRRICQSVVLLLGG-----TACLIIPAIPAKYPIVVTVIAVIGKFSLA 429

  Fly   431 VSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGAGL 495
            .|:.....|.||:.||.||...|....:....:..||..:..|..|:..:|.|....|.|.|..|
Zfish   430 ASFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSLPFVGGAL 494

  Fly   496 CLTLPETLNKKLPE 509
            ...||||||..|.:
Zfish   495 TFLLPETLNTDLQD 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	130/524 (25%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	96/381 (25%)
slc22a13b	XP_017209322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588882
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950