DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and CG6356

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	567	Identity:	134/567 - (23%)
Similarity:	225/567 - (39%)	Gaps:	105/567 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTP-EHWC----------FHADLNGLSVE 60
            |:..|:.|.|...|..|....|||...|..|.||:...| :.||          .||....:..:
  Fly    28 LEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIVAK 92

  Fly    61 GIRS----------------VYENISASSCTPLLGVVNGTGVVSTNRKCRNWIFNRESGYESITT 109
            |:.|                .||  :|.:.|..|..::....||...|.::     |..:...|.
  Fly    93 GLDSGGCTVWDWNYGHLAKMSYE--AALNYTGHLTQISPPAEVSCRVKGQH-----EFAHPETTF 150

  Fly   110 ELKW--VCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTL 172
            ...|  .||:|......|....:|...|:..||.|:|:.||..|..:.......|.|..:|   .
  Fly   151 VADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTF---S 212

  Fly   173 PWFAF---SRFMSGLSTDTMYYLMYILVFEYLSPKSRTF-----------GLNIILAVFYCFGLM 223
            ||::.   .||..|.::..::|..:.::.|.:..|.|::           |: ||||:   .|.:
  Fly   213 PWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGM-IILAI---VGYV 273

  Fly   224 TSPWAAIWIGNWRRYLWLA-SLPALGVLIYPFLICESAQWLLTKRKYD----------------D 271
            ..||         |:|.|| ::|:|.:::..:|:.||.:||:|.::||                .
  Fly   274 IQPW---------RHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQP 329

  Fly   272 AVICLKKVAKFNRRHVEESVFDEFVKYYRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKS 336
            ||....:||. :::.:|......|     .::|::..|.|    .:.::...::||.........
  Fly   330 AVAAPSQVAS-DKKSLEPEEGFSF-----GQKLKNGPLKS----IIELYANSKVRRMIFASYFMF 384

  Fly   337 VIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTA 401
            .:.:||..|...|...|..|.:.....|.:|.:|:.:..:::....||:   .|.:|:  .:.|.
  Fly   385 CVTSLSYYVTALNAANLSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRR---LTTMFL--FLWTG 444

  Fly   402 TGFMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSL 466
            ...::....|..:...:.....|||||.:.:|.....|.||:.||.:|..|:..........|..
  Fly   445 VSLLLVLAVPAGSTTWIVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSIS 509

  Fly   467 AFYVI----YLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPE 509
            |.||:    .|..|   :|:....|.:.....|.||||||...||.:
  Fly   510 APYVVDVLGALGWY---IPTTICGCCVLVAGLLTLTLPETGTGKLSD 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	133/563 (24%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	92/407 (23%)
CG6356	NP_651240.1	MFS	167..544	CDD:119392	94/410 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458480
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	4.940