DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and Orct

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	554	Identity:	153/554 - (27%)
Similarity:	251/554 - (45%)	Gaps:	70/554 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSV 65
            |.:..|:...|.:|.:|..|..|.....|:.:.|..:...:...|:..|.....||       |:
  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENG-------SI 58

  Fly    66 YE------NIS---ASSCTPLLGV------VNGTGVVSTN--RKCRNWIFNRESGYESITTELKW 113
            ||      |:|   ...|: ...|      :||:...|:|  :.|.:::::|.....|..||...
  Fly    59 YELSPHLWNLSYPENERCS-YYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNL 122

  Fly   114 VCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPS--------LLMATLCGATGDFITSFVH 170
            ||.:|...|...|.|.:|.::|::|||.:||::||.|:        |:...|.....::.:
  Fly   123 VCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFS---- 183

  Fly   171 TLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNW 235
                :..||.:.|.:|..::.:.|::..|.:....|.|. .:.:.:|:..|.|.:...|.:|.:|
  Fly   184 ----YTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFA-GVAMQMFFSVGFMLTAGFAYFIHDW 243

  Fly   236 RRYLWL---ASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVK 297
            |   ||   .:||.|..|.|.::|.|||:|||.|.:.|:|.:.::|.||.|:..|...::::.|.
  Fly   244 R---WLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVD 305

  Fly   298 YYRERELQDYKLNSH-EDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLF 361
            ...|::.||....|. ..|...:...|.|||.||.:.....:.:.....::.|...||.:....|
  Fly   306 EVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNF 370

  Fly   362 SFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGR 426
            ..:..|.:|....:|...|:.||:.:.|..:.|.|:...||.|:     |::...|:.....:|:
  Fly   371 MISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFV-----PSDMNWLIVACAMIGK 430

  Fly   427 FGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSS--------LAFYVIYLAQYYKPLPSI 483
            ...|.||.....::||..||.||.        :||.:||        ||.|:..|.:.::|||.|
  Fly   431 LAITSSYGTIYIFSAEQFPTVVRN--------VGLGASSMVARVGGILAPYLKLLGEIWRPLPLI 487

  Fly   484 FISCLMFFGAGLCLTLPETLNKKLPETLADGEKF 517
            ....|......|.|.|||||||.:|||:.|||.|
  Fly   488 ICGALSLTAGLLSLLLPETLNKPMPETIEDGENF 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	145/535 (27%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	106/392 (27%)
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	145/535 (27%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	103/380 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458408
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	4.940