DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and CG7084

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	585	Identity:	141/585 - (24%)
Similarity:	246/585 - (42%)	Gaps:	109/585 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FSQVLDKCGNYGRFQVMILLLY-GYTNILGSLHYFSQTLITFTPEHWCF---------------- 50
            |..:::|.||:||:|.:...:: |.....|::.|.:..|....|:|||.
  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIPDHWCTVPGRENTNFSLEEWRD 98

  Fly    51 -----HADLNGLSVEGIRSVYEN-----ISASSCTPLLGVVNGTGVVSTNRKCRN-WIFNRESGY 104
                 .||..|      |..:.|     ::.|..|.....  .:.:..|...|:| |.::: :.|
  Fly    99 ITLPKQADNRG------RKTFSNCEMFQMNFSEITDWSAW--NSNLTKTTEACQNGWSYDK-TWY 154

  Fly   105 ES-ITTELKWVCDKSHHPAVGQSFFFMG---SVVGTIIFGYLSDQVGR----LPSLLMATLCGAT 161
            || |.|:..|||.|.   ....:.|.:|   .|.|:.|.|.:.|..||    ..|::..:| |..
  Fly   155 ESTIPTDHNWVCAKD---LFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSL-GRL 215

  Fly   162 GDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVF----YCFGL 222
            |..:.:..:|  ||.....:.||:.::::....|:..|....:.|:     .:|.|    :..|.
  Fly   216 GSIMCTSSYT--WFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRS-----RIAFFQSCGWSIGT 273

  Fly   223 MTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHV 287
            ...|....|:.:|..::||.|:|...||::...:.||.:||::|:::.:|::.|:|:||.|...
  Fly   274 TLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHR- 337

  Fly   288 EESVFDEFVKYYRERELQD-YKLNSHEDTF--LAMFLTPRLRRFTLTLLVKSVIITLSCDVINRN 349
                ||     ..|:||.: |..:..:.|:  .::|...||.|.|..:.....::.:|...:...
  Fly   338 ----FD-----MTEKELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLF 393

  Fly   350 MEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHL----- 409
            ...:..:||..|.:.|||.:||.|....:.:..||:            .|.:..|:|:.:
  Fly   394 SSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRR------------FTNSVSFLISFVTCLPI 446

  Fly   410 -----DPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFY 469
                 |.....|::.:...:....|...:...:| ..||.||.:|...|:...::..|...||.|
  Fly   447 IVYSTDERYENLMIYLATFIKFLNALTFFTVNLQ-CLEIYPTCMRQTGVALGTILANAIGVLAPY 510

  Fly   470 VIYL-------AQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYFP 527
            ::||       |.||      .:..|...|....|.|||||:||||:|:.:...|..::.|...|
  Fly   511 LVYLGTTVDIRAPYY------ILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLP 569

Fly 528 527
Fly 570 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	135/558 (24%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	93/403 (23%)
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	128/536 (24%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	91/394 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	4	4.010