DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and CG6231

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster

Alignment Length:	544	Identity:	252/544 - (46%)
Similarity:	364/544 - (66%)	Gaps:	9/544 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSV 65
            |||.|:|.|||::.|:|.|||.|:|:.||:.|:|||:||:|:|.|:|||:|..|..::.:.|..:
  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMTYKEIGEI 65

  Fly    66 YENISASSCTPLLGVVNGTGVVSTNRKCRNWIFNRESGYESITTELKWVCDKSHHPAVGQSFFFM 130
            |......||| .|..:||..|..:::.|..||:|.:.||.|:.|||.||||.::...:|||.||:
  Fly    66 YAQFENPSCT-RLDDINGHNVTVSSKACEKWIYNYDFGYRSMNTELNWVCDSAYKARIGQSLFFI 129

  Fly   131 GSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYI 195
            ||||||:.:|.|||::||:|:|:::..||..|||.|.|..::..|...||:|||:.||.:|||||
  Fly   130 GSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYI 194

  Fly   196 LVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESA 260
            :|.||:.|..||.|||:.:.:|||.||:.:||.|:.:|:|:.||...|||.|.|::|.|::.|||
  Fly   195 IVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESA 259

  Fly   261 QWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERELQDYKLNSHED----TFLAMFL 321
            |||:|:...|.|::.||:|||||...|.::.||||.::.:    ..:::...:|    |.|.||.
  Fly   260 QWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQ----MTHEMLGGDDKKQATLLDMFR 320

  Fly   322 TPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKG 386
            |||:|:.||.|..||::|||..|.::||:||:|.|||.:||.:::..||:.|.::|||::|||||
  Fly   321 TPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSALAVLPSSVLLVLLQDRIGRKG 385

  Fly   387 MACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQ 451
            ||..:|.||||.|.|.|..||:.....||:|||.:....|||..:||::..|||.|:|||.||||
  Fly   386 MASGSLLVGGLFTAAAGIAIAYQQHNHNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQ 450

  Fly   452 AVSNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEK 516
            .|:.:||.|.|:|.||.|:::|..::|..|||.:..|.|.|:.:||.||||||:.||.|:.:||.
  Fly   451 GVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGEV 515

  Fly   517 FALNESFLYFPCFSRKEKNVRTES 540
            |...|....|||...|..:..:||
  Fly   516 FGKGERMFDFPCLHNKHDDEESES 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	234/502 (47%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	177/376 (47%)
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	234/502 (47%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	177/377 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471391
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	9	8.860