DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and CG17752

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_650817.1	Gene:	CG17752 / 42337	FlyBaseID:	FBgn0038718	Length:	538	Species:	Drosophila melanogaster

Alignment Length:	544	Identity:	322/544 - (59%)
Similarity:	412/544 - (75%)	Gaps:	20/544 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSV 65
            ||..:||:||||:|.:|:::|.|||||||:.||||||||||:|||.|.|      ...||.....
  Fly     1 MDLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRC------SAPVEEFSQN 59

  Fly    66 YENISASSCTPLLGVVNGTGVVSTNRKCRNWIFNRESGYESITTELKWVCDKSHHPAVGQSFFFM 130
            :..:  .||:.:...|:.|..  .:.||.:|.|::||.||||||||:||||.::..||||||||:
  Fly    60 FTEL--LSCSVIQYDVDMTSF--RDNKCSSWDFDKESNYESITTELEWVCDDAYKLAVGQSFFFI 120

  Fly   131 GSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYI 195
            ||.:|:|.||||:|::||||:.:::||.||:|||.||||.:||.|:|:||:||||.||.|.||||
  Fly   121 GSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPMFSFTRFISGLSMDTQYVLMYI 185

  Fly   196 LVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESA 260
            ||||||||:.|||||||||.|||..|||.|||.|||:||||.|||.|||||||:||:|..:.||.
  Fly   186 LVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSYLWAASLPALGMLIFPLFLHESV 250

  Fly   261 QWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERELQDYKLNSHE----DTFLAMFL 321
            :|||||.|:|.||..||.|||||.|.||:||||||:|:|||      ||||.:    |||:.|..
  Fly   251 EWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYRE------KLNSAQKKSSDTFMGMLR 309

  Fly   322 TPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKG 386
            |||||:||:.||:||:|||::.|:::||:||:|.|||||||::..|.||.|::|:|.||||||||
  Fly   310 TPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFVVLPGGLSIILFQNKIGRKG 374

  Fly   387 MACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQ 451
            |||.:|.||..||..||:::..|||...::||..||.|.||||.|:||||.|||||||||||||:
  Fly   375 MACASLLVGAFITATTGYLVGTLDPANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGR 439

  Fly   452 AVSNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEK 516
            .|:||||:|.|.:..:.|:|||..:||||||:.||.|:..||.|||||||||:|:||:||.:||.
  Fly   440 GVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLLISFLLIIGACLCLTLPETLHKQLPQTLEEGEI 504

  Fly   517 FALNESFLYFPCFSRKEKNVRTES 540
            ||..|.:.:|||||||.::.::||
  Fly   505 FAKGEKWYFFPCFSRKRQSNKSES 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	300/502 (60%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	236/376 (63%)
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	300/502 (60%)
CG17752	NP_650817.1	MFS	116..488	CDD:119392	237/377 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471372
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.850