DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and CG8925

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_650526.1	Gene:	CG8925 / 41963	FlyBaseID:	FBgn0038404	Length:	670	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	122/532 - (22%)
Similarity:	211/532 - (39%)	Gaps:	112/532 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 FQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHAD-LNGLSVEGIRSVYENISASSCTPLLG 79
            :|.|...|......:.:.|.|.........:.||...: |..:||    |.:.|||.||...||.
  Fly   160 WQSMWCALLSIFQAICTFHIFVYVFQIAPKDFWCARPENLMQMSV----SEWRNISQSSNGCLLL 220

  Fly    80 VVNGTGVVSTNRKCRNWIFN-RESGY---------------ESITTELKWVCDKSHHPAVGQSFF 128
            .|:.|.|...|.:..||..| .:.||               :::..|...||.:.....| ::.|
  Fly   221 DVDYTQVTYENNQLINWPENATDLGYRQCWHFEFSDVDGSAKTLVQEFDLVCGRDILSLV-ETCF 284

  Fly   129 FMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLM 193
            .:|:..|.::.|::||:.||..:|:......:....|.:|..::..|...|.:.|.::.|:..:.
  Fly   285 LVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSVFGGILAFSTSVAMFMSLRVIIGFASMTVTVVS 349

  Fly   194 YILVFEYLSPKSRT-FG-LNII-LAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFL 255
            ::||.|.:|.|.|| .| |||: :|:.|    :.|...|..|.:||......|.|.|.:|...|.
  Fly   350 FVLVVELVSGKWRTVIGILNILPVAISY----VLSAGLAYLIRDWRHLQLAISWPWLIMLSIWFW 410

  Fly   256 ICESAQWLLTKRKYDDAVICLKKVAKFN----------RRHVE--------------ESVFDEFV 296
            :.||.:|||.:.:.|:....:::.|:.|          |:.:|              .||..:.|
  Fly   411 LPESPRWLLAQGRLDELCGLIERAARMNGTSASLPSNYRKTLEAAVPRAVQSPPEATTSVESKAV 475

  Fly   297 KYYRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLF 361
                |.:..|...:.|.:..|.:|.....|...|||::...:|.:... :..::..||.:
  Fly   476 ----EADAPDPSASGHVNPLLVVFSAKYWRTTCLTLVIWLTLIIIYFG-LTLHLSNLGGN----- 530

  Fly   362 SFTSIVYLPAGVA----------ILLLQNKIGRK----------GMACTALFVGGLITTATGFMI 406
                 :|:.:.||          .:|:..|:|.:          |:.|.|.   .|::..||.:
  Fly   531 -----IYINSAVAGTVEAISICISILVVLKVGIRRSLIGYMLLPGLCCLAT---NLVSNQTGVI- 586

  Fly   407 AHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVI 471
                    ||.......:|...|.:.....:||     ||.||...|.    :|..:|.:|..::
  Fly   587 --------ALATIAKCLIGANNAIIPTYTAMQY-----PTIVRNFGVG----MGNLASGIALILV 634

  Fly   472 ---YLAQYYKPL 480
               :..::..||
  Fly   635 PFLWKLEHIDPL 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	122/532 (23%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	91/405 (22%)
CG8925	NP_650526.1	MFS	277..667	CDD:119392	92/411 (22%)
CG8925	NP_650526.1	MFS_1	277..635	CDD:284993	90/398 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	4	4.010