DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and CG14856

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	200/529 - (37%)
Similarity:	319/529 - (60%)	Gaps:	4/529 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSV 65
            |||.::|.|||:..|:|.|:|.|||....:.|.|||:|.:|.|.|:|||:|..|...|...|.::
  Fly     3 MDFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLENRSYAEIAAI 67

  Fly    66 YENISASSCTPLLGV-VNGTGVVSTNRKCRNWIFNRESGYESITTELKWVCDKSHHPAVGQSFFF 129
            |......|||.|..: ::|:...:::..|..||::.:.|:.|:..:|.||||.::...||||.||
  Fly    68 YAPFKRPSCTRLASINMDGSNATASSEPCNRWIYHYDHGFISMNADLNWVCDDAYKARVGQSLFF 132

  Fly   130 MGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMY 194
            :||:.||::||.|.|::||:.::::|..||..||..|.|..||..|:.|||:|||:.:...|||:
  Fly   133 VGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLTFSASRFVSGLAAEANSYLMF 197

  Fly   195 ILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICES 259
            |||.||:||..|:.|||:.:.|||..|::.:.|..:|:|:||.::...:||.|.|..:.|||.||
  Fly   198 ILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQES 262

  Fly   260 AQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKY--YRERELQDYKLNSHEDTFLAMFLT 322
            ||||:|::.:|.|.:.|::|||||||.|.|:.::.|.::  .:|.|.:.......:...:..|..
  Fly   263 AQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKESEARSQMSMQKQARLIDSFKL 327

  Fly   323 PRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGM 387
            ||||...:.:.|...|:||..:.::||:|||..|||.:||..::...|:|:....:|...|||..
  Fly   328 PRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFT 392

  Fly   388 ACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQA 452
            :..::...||:|..||.::|.. ...:|.::..::.:.|||.:|:..:.:|.:.|::||.||...
  Fly   393 SVVSMTATGLMTATTGILLAFW-TQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSG 456

  Fly   453 VSNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKF 517
            ::.|||...|.|.::.::::|..|::...||....|:...|.:||.|.||.|||||.|||:||:|
  Fly   457 LAVIHVTAAALSFISPFILHLDTYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEF 521

  Fly   518 ALNESFLYF 526
            ...|....|
  Fly   522 GKGERMFDF 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	186/501 (37%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	136/374 (36%)
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	186/501 (37%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	136/374 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471389
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.860